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anti-Rat (Rattus) AXIN1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended AXIN1 Antibody (supplied by: Log in to see )

Antigen
Axin 1 (AXIN1) Antibodies
  • AI316800
  • Axin
  • AXIN
  • axin
  • AXIN1
  • AXIN1-RGS
  • Fu
  • fused
  • Kb
  • Ki
  • kinky
  • knobbly
  • LOC100226467
  • PPP1R49
  • wu:fi22e03
  • wu:fj14c08
  • wu:fk11b03
  • xAxin
  • zgc:109872
Epitope
AA 830-862
49
19
16
15
15
12
10
4
3
3
2
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
128
35
27
5
4
2
1
1
1
1
1
Host
Rabbit
87
29
19
Clonality
Polyclonal
Conjugate
This AXIN1 antibody is un-conjugated
8
8
6
6
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
80
31
26
20
19
14
10
4
1
Supplier
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Catalog No. ABIN740295
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000883307 ABIN884285 IF (p) Alexa Fluor 350 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN884289 IF (p) Alexa Fluor 647 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN884286 IF (p) Alexa Fluor 488 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN884288 IF (p) Alexa Fluor 555 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN740298 IF (p) Cy3 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN740299 IF (p) Cy5 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN740301 IF (p) Cy7 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN740302 IF (p) FITC Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN740300 IF (p) Cy5.5 Rabbit IgG AA 830-862 Log in to see Polyclonal
0.000883307 ABIN2810113 IF (p) Alexa Fluor 594 Rabbit IgG AA 830-862 Log in to see Polyclonal

Similar anti-AXIN1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 9 Antibodies 11 Antibodies 79 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 3 Antibodies
Immunofluorescence (IF) 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 6 Antibodies
Western Blotting (WB) 12 Antibodies 19 Antibodies
Dot Blot (DB) 1 Antibodies

General

Antigen Axin 1 (AXIN1) Antibodies
Epitope AA 830-862
(49), (19), (16), (15), (15), (12), (10), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(128), (35), (27), (5), (4), (2), (1), (1), (1), (1), (1)
Host Rabbit
(87), (29), (19)
Clonality
Polyclonal
Conjugate This AXIN1 antibody is un-conjugated
(8), (8), (6), (6), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(103), (80), (31), (26), (20), (19), (14), (10), (4), (1)
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Product Details anti-AXIN1 Antibody

Target Details AXIN1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Axin1
Isotype IgG

Target Details AXIN1

Product Details anti-AXIN1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Axin1 (AXIN1 Antibody Abstract)
Background

Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.

Subcellular location: Cytoplasm, Nucleus


Synonyms: AXIN, PPP1R49, Axin-1, Axis inhibition protein 1, hAxin, AXIN1
Gene ID 8312
UniProt O15169
Pathways WNT Signaling

Application Details

Product Details anti-AXIN1 Antibody Target Details AXIN1 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-AXIN1 Antibody Target Details AXIN1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-AXIN1 Antibody Target Details AXIN1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-AXIN1 antibody (Axin 1) (AA 830-862) (ABIN740295) Lane 1: mouse heart probed with Rabbit Anti-Axin1 Polyclonal Antibody, Unconjugated (...