|Antigen||Frizzled Family Receptor 10 (FZD10) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This FZD10 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-FZD10 AntibodyTarget Details FZD10 Application Details Handling Images
|Specificity||This antibody detects endogenous levels of Frizzled-10 protein.(region surrounding Leu164)|
|Purification||Affinity Chromatography using epitope-specific immunogen.|
Target Details FZD10Product Details anti-FZD10 Antibody Application Details Handling Images back to top
|Alternative Name||CD350 / FZD10 / Frizzled-10 (FZD10 Antibody Abstract)|
|Background||This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.Frizzled 10 is expressed during development in embryonic limbs, neural tube, and central nervous system. It has been reported to be expressed in brain, embryo, kidney, liver, lung and pancreas.Synonyms: Fz-10, FzE7, hFz10|
|Molecular Weight||approx. 60 kDa|
Application DetailsProduct Details anti-FZD10 Antibody Target Details FZD10 Handling Images back to top
ELISA: 1/5000-1/10000. Wetern Blot: 1/500-1/1000. Immunofuorescence: 1/50-1/200. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
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|Buffer||Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
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