|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)||Cow (Bovine)||Dog (Canine)|
|Western Blotting (WB)||40 Antibodies||23 Antibodies||14 Antibodies||3 Antibodies||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||17 Antibodies||6 Antibodies||3 Antibodies||1 Antibodies||1 Antibodies|
|Immunohistochemistry (IHC)||22 Antibodies||9 Antibodies||6 Antibodies||2 Antibodies||2 Antibodies|
|Immunofluorescence (IF)||6 Antibodies||2 Antibodies|
|Antigen||Frizzled Family Receptor 8 (FZD8) Antibodies|
|Reactivity||Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This FZD8 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-FZD8 AntibodyTarget Details FZD8 Application Details Handling Images
|Specificity||This antibody reacts to Frizzled-8.|
Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.
|Immunogen||Peptide with sequence C-SYPKQMPLSQV, from the C Terminus of the protein sequence|
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|Alternative Name||FZD8 / Frizzled-8 (FZD8 Antibody Abstract)|
|Background||Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.Synonyms: Fz-8, hFz8|
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Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FZD8 Antibody Target Details FZD8 Application Details Images back to top
|Buffer||Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
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