14-3-3 Protein beta/alpha Protein (1433B) (AA 1-246, full length) (GST tag)
This Recombinant 14-3-3 Protein beta/alpha protein is produced in Escherichia coli (E. coli).
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Catalog No. ABIN5712159
Quick Overview for 14-3-3 Protein beta/alpha Protein (1433B) (AA 1-246, full length) (GST tag) (ABIN5712159)
Target
14-3-3 Protein beta/alpha (1433B)
Protein Type
Recombinant
Origin
Human
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
Purity
> 90 %
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Protein Characteristics
- full length, AA 1-246
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Purification tag / Conjugate
- This 14-3-3 Protein beta/alpha protein is labelled with GST tag.
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Sequence
- MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 14-3-3 Protein beta/alpha (1433B)
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Alternative Name
- 1433B
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Background
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
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Molecular Weight
- 55.5 kDa
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UniProt
- P31946
Target
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