Acetyl-CoA Acetyltransferase 1 Proteins (ACAT1)

The protein encoded by ACAT1 belongs to the acyltransferase family. Additionally we are shipping ACAT1 Antibodies (188) and ACAT1 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACAT1 38 P24752
ACAT1 25014 P17764
ACAT1 110446 Q8QZT1
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Top ACAT1 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$400.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human ACAT1 Protein. 100 μg Log in to see 11 to 18 Days
$412.19
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$3,067.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,067.17
Details
Yeast Cynomolgus His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details

ACAT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Acetyl-CoA Acetyltransferase 1 (ACAT1) Interaction Partners

Human Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase.

  2. compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient

  3. Data indicate that acetyl-CoA (show LPCAT2 Proteins) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Proteins)) are involved in various drug-resistance-forming mechanisms.

  4. ACAT1, ACACA (show ACACA Proteins), ALDH6A1 (show ALDH6A1 Proteins) and MTHFD1 (show MTHFD1 Proteins) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.

  5. the pyruvate dehydrogenase (show PDP Proteins) complex is regulated by Tyr (show TYR Proteins) phosphorylation of PDP1 (show PDP Proteins), which toggles recruitment between ACAT1 and SIRT3 (show SIRT3 Proteins)

  6. these findings indicate that ACAT1 expression could serve as a potential prognostic marker in prostate cancer, specifically in differentiating indolent and aggressive forms of cancer.

  7. ACAT1 expression is substantially elevated in human castration-resistant metastatic prostate cancer tissues.

  8. Data show that the ketone body metabolizing enzymes BDH1 (show BDH1 Proteins), BDH2 (show BDH2 Proteins), OXCT1 (show OXCT1 Proteins) and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines.

  9. Crystallographic and kinetic studies were made on mitochondrial acetyl-CoA (show LPCAT2 Proteins) thiolase (show HADHB Proteins): the importance of potassium and chloride ions were noted for its structure and function.

  10. I/D polymorphism of ACE (show ACE Proteins) gene and AC AT1 (show AGTR1 Proteins) gene influence the development of hypertension and Left Ventricular Hypertrophy in Hemodialysis patients.

Mouse (Murine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. Data show that microRNA miR (show MLXIP Proteins)-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 (show SOAT1 Proteins) 3' untranslated regions (3'UTR).

  2. In a mouse model, targeting ACAT1 (show SOAT1 Proteins) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.

  3. Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Proteins)/MyD88 (show MYD88 Proteins)/NF-kappaB (show NFKB1 Proteins) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Proteins) expression and promotes VSMC foam cell formation.

  4. Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Proteins) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Proteins) signaling.

  5. ACAT1 (show SOAT1 Proteins) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Proteins)(-/-) mouse during atherosclerosis development.

  6. ApoA-I (show APOA1 Proteins) Helsinki promotes accumulation of ACAT1 (show SOAT1 Proteins) in a mouse macrophage cell line.

  7. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Proteins) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Proteins)

  8. ACAT1 (show SOAT1 Proteins) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.

  9. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol

  10. ACAT1 (show SOAT1 Proteins) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.

Cow (Bovine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. The transcript abundance of ACAT1 was increased in the more efficient low residual feed intake (RFI (show RNF34 Proteins)) animals and decreased in the less efficient high RFI (show RNF34 Proteins) animals

ACAT1 Protein Profile

Protein Summary

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Gene names and symbols associated with ACAT1

  • acetyl-CoA acetyltransferase 1 (ACAT1)
  • acetyl-CoA acetyltransferase 1 (Acat1)
  • acetyl-Coenzyme A acetyltransferase 1 (Acat1)
  • acetyl-CoA acetyltransferase 1 (acat1)
  • acetyl-CoA acetyltransferase 1 L homeolog (acat1.L)
  • 6330585C21Rik protein
  • Acat protein
  • acat1-a protein
  • fd16h07 protein
  • fd20g06 protein
  • MAT protein
  • RATACAL protein
  • T2 protein
  • THIL protein
  • wu:fd16h07 protein
  • wu:fd20g06 protein
  • zgc:86832 protein

Protein level used designations for ACAT1

acetoacetyl Coenzyme A thiolase , acetoacetyl-CoA thiolase , acetyl-CoA acetyltransferase, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 , mitochondrial acetoacetyl-CoA thiolase , acetyl-Co A acetyltransferase 1 mitochondrial , acetyl-coenzyme A acetyltransferase 1 , acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) , acetyl-CoA acetyltransferase 1 , Acetoacetyl-CoA thiolase A , acetyl-CoA acetyltransferase A, mitochondrial

GENE ID SPECIES
38 Homo sapiens
25014 Rattus norvegicus
110446 Mus musculus
418968 Gallus gallus
445290 Danio rerio
489421 Canis lupus familiaris
511082 Bos taurus
100597123 Nomascus leucogenys
100626793 Sus scrofa
414639 Xenopus laevis
100717423 Cavia porcellus
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