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APLNR encodes a member of the G protein-coupled receptor gene family. Additionally we are shipping Apelin Receptor Antibodies (165) and Apelin Receptor Proteins (5) and many more products for this protein.
Showing 6 out of 19 products:
Rat (Rattus) Apelin Receptor ELISA Kit for Sandwich ELISA - ABIN433383
Mahmoody, Gharakhanlou, Roshan, Hedayati: Individual and concomitant effects of cardioprotective programs on cardiac apelinergic system and oxidative state in L-NAME-induced hypertension. in Clinical and experimental hypertension (New York, N.Y. : 1993) 2012
APJ receptor in granulosa cells and both apelin (show APLN ELISA Kits) and the APJ receptor in theca tissues are expressed in bovine ovary.
The data suggest that apelin (show APLN ELISA Kits)/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.
The ELA-APJ axis protects from pressure overload-induced heart failure possibly via suppression of ACE (show ACE ELISA Kits) expression and pathogenic angiotensin II signaling.
Internalization does not appear to contribute to the desensitization of APJ-mediated ppERK1/2 activation.
the ELABELA (ELA)-APJ signaling axis is only required for sinus venosus-derived progenitors.
These results demonstrate a new pharmacologic property of protamine-blockade of APJ-that could explain some adverse effects observed in protamine-treated patients, and that the established antiangiogenic activity of protamine would rely on APJ antagonism.
Apelin (show APLN ELISA Kits)-36-[L28C(30kDa-PEG (show PAEP ELISA Kits))] provides a starting point for the development of diabetes therapeutics that are devoid of the blood pressure effects associated with canonical APJ activation
Results show that obese mice had significantly lower mRNA and protein expressions of apelin (show APLN ELISA Kits)/ APJ in skeletal muscles than the normal body weight mice.
These results demonstrate that overexpression of APJ in cardiomyocytes has adverse effects on cardiac function in male and non-pregnant mice and that lactation contributes to the development of postpartum cardiomyopathy in the heart with APJ overexpression.
Endothelial CXCR4 (show CXCR4 ELISA Kits) is negatively regulated by miR (show MLXIP ELISA Kits)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN ELISA Kits)/APLNR signalling.
apelin (show APLN ELISA Kits) is produced by arterial endothelial cells (ECs) during embryogenesis, induces chemotaxis of venous ECs, and promotes the production of secreted Frizzled-related protein 1 (show SFRP1 ELISA Kits) by apelin receptor(+) ECs
Findings demonstrate a stimulatory role for the islet cell apelin (show APLN ELISA Kits)-APJ signaling axis in regulation of pancreatic islet homeostasis and in metabolic induced beta-cell hyperplasia.
Studies suggest that apelin (show APLN ELISA Kits)/APJ system may be applied to the treatment of cancers by regulating apoptosis, which may play a vital role in anticancer therapy [review].
Crystal structure of human APJR shows structural basis for apelin (show APLN ELISA Kits) recognition and binding
mutation of promoter polymorphism rs7119375 in APJ gene was significantly associated with elevated SBP (show SHBG ELISA Kits) and increased hypertension risk in Chinese women.
The APLNR A445C polymorphism was not associated with diabetic retinopathy in a sample of the Tunisian population, but the CC genotype carrier patients with DR had a high total cholesterol concentration.
APLN (show APLN ELISA Kits) and APLNR are present in human ovarian cells and APLN (show APLN ELISA Kits) increases IGF1 (show IGF1 ELISA Kits)-induced steroidogenesis in granulosa cells through an increase in HSD3B (show HSD3B1 ELISA Kits) protein expression and activation of the MAPK3 (show MAPK3 ELISA Kits)/1 and Akt (show AKT1 ELISA Kits) pathways. Therefore, APLN (show APLN ELISA Kits) and APLNR may play a role in human follicular development and the pathogenesis of PCOS.
The apelin (show APLN ELISA Kits)/APLNR axis regulates cholangiocarcinoma cell proliferation and tumor angiogenesis.
Data suggest that the differential expression of Apelin (show APLN ELISA Kits) and Apelin receptor APJ yields a "self-generated" gradient mechanisms that accelerates the extension of the sprout.
The aim of this study was to evaluate if polymorphisms of APLN (show APLN ELISA Kits) and APLNR genes may play a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients.
review of the important role of the Apelin (show APLN ELISA Kits)/APJ system in pathological angiogenesis
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
angiotensin II receptor-like 1
, G-protein coupled receptor APJ
, angiotensin receptor-like 1
, angiotensin receptor-related protein
, apelin receptor
, APJ (apelin) receptor
, APJ receptor
, G protein-coupled receptor APJ
, G-protein coupled receptor HG11
, HG11 orphan receptor