C-Type Lectin Domain Family 14, Member A Proteins (CLEC14A)

CLEC14A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC14A Antibodies (55) and CLEC14A Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLEC14A 161198 Q86T13
CLEC14A 66864 Q8VCP9
CLEC14A    
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Top CLEC14A Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Human Cells Mouse His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Human Cells Rat Fc Tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

CLEC14A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for C-Type Lectin Domain Family 14, Member A (CLEC14A) Interaction Partners

Human C-Type Lectin Domain Family 14, Member A (CLEC14A) interaction partners

  1. These findings identify novel protein interactions involving CLEC14A, CD93 (show CD93 Proteins) and CD248 (show CD248 Proteins) with MMRN2 (show MMRN2 Proteins) as targetable components of vessel formation

  2. The CLEC14A-MMRN2 (show MMRN2 Proteins) interaction is involved in sprouting angiogenesis. Disrupting this interaction with monoclonal antibodies directed against CLEC14A show anti-angiogenic and anti-tumor effects.

  3. CLEC14A is a matrix component which binds to MMRN2 (show MMRN2 Proteins) in the process of endothelial cells transformation in tumor angiogenesis.

  4. clec14a-CTLD may be a key domain in angiogenesis

  5. In this study, they identify and characterize a novel tumor endothelial marker, CLEC14A, which has properties that suggest it is a candidate for tumor vascular targeting and anti-angiogenic approaches.

Mouse (Murine) C-Type Lectin Domain Family 14, Member A (CLEC14A) interaction partners

  1. CLEC14A acts in vascular homeostasis by fine-tuning VEGFR-2 (show KDR Proteins) and VEGFR-3 (show FLT4 Proteins) signaling in endothelial cells

  2. clec14a-CTLD may be a key domain in angiogenesis

  3. These findings demonstrate that Clec14a is a novel endothelial cells specific protein that appears to play a role in cell-cell adhesion and angiogenesis.

CLEC14A Protein Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.

Gene names and symbols associated with CLEC14A

  • C-type lectin domain containing 14A (CLEC14A)
  • C-type lectin domain family 14, member a (Clec14a)
  • 1200003C23Rik protein
  • AI642649 protein
  • C14orf27 protein
  • CEG1 protein
  • EGFR-5 protein

Protein level used designations for CLEC14A

C-type lectin domain family 14 member A , ClECT and EGF-like domain containing protein , epidermal growth factor receptor 5

GENE ID SPECIES
161198 Homo sapiens
66864 Mus musculus
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