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anti-CUB Domain Containing Protein 1 (CDCP1) Antibodies

The protein encoded by CDCP1 is a transmembrane protein containing three extracellular CUB domains. Additionally we are shipping CUB Domain Containing Protein 1 Proteins (19) and CUB Domain Containing Protein 1 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDCP1 64866 Q9H5V8
CDCP1 109332 Q5U462
CDCP1 301082  
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Top anti-CUB Domain Containing Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184664 (1µg/ml) staining of Human Colon lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.62
Details
Human Rabbit Un-conjugated IHC (p), WB CDCP1 was detected in paraffin-embedded sections of human placenta tissues using rabbit anti- CDCP1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). CDCP1 was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- CDCP1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from COLO205 cells, using CDCP1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using CDCP1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using CDCP1 mAb against human CDCP1 (AA: 692-836) recombinant protein. (Expected MW is 42 kDa) 0.1 mg Log in to see 8 to 11 Days
$561.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Colon, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$181.73
Details
Human Goat Un-conjugated ELISA, WB ABIN257697 staining (1ug/ml) of human colon extracts (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence Western Blot: CDCP1 Antibody [ABIN257697] - (1ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD318 expression in HeLa (A), DU145 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD318 (pY707) expression in HeLa UV-treated (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: CDCP1 Antibody [NBP1-85759] - Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and extracellular material of glandular lumina. Immunohistochemistry-Paraffin: CDCP1 Antibody - Staining of human esophagus shows high expression. 0.1 mL Log in to see 7 to 9 Days
$491.63
Details

Top referenced anti-CUB Domain Containing Protein 1 Antibodies

  1. Human Polyclonal CDCP1 Primary Antibody for ELISA, WB - ABIN257697 : Hooper, Zijlstra, Aimes, Liang, Claassen, Tarin, Testa, Quigley: Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. in Oncogene 2003 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CDCP1 Primary Antibody for CyTOF, FACS - ABIN4900572 : Kelly, Chan, Martinson, Kadoya, Ostertag, Ross, Richardson, Carpenter, DAmour, Kroon, Moorman, Baetge, Bang: Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. in Nature biotechnology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal CDCP1 Primary Antibody for IHC, IHC (p) - ABIN4296996 : Iwata, Torok-Storb, Wayner, Carter: CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production. in PLoS ONE 2014 (PubMed)

More Antibodies against CUB Domain Containing Protein 1 Interaction Partners

Human CUB Domain Containing Protein 1 (CDCP1) interaction partners

  1. Co-expression of CDCP1 and AXL (show AXL Antibodies) is often observed in EGFR (show EGFR Antibodies)-mutation-positive tumors, limiting the efficacy of EGFR (show EGFR Antibodies) TKIs. Co-treatment with EGFR (show EGFR Antibodies) TKI and TPX (show TPO Antibodies)-0005 warrants testing.

  2. CDCP1 knockdown reduced 3D invasion, which can be rescued by ACSL3 (show Acsl3 Antibodies) co-knockdown. In vivo, inhibiting CDCP1 activity with an engineered blocking fragment (extracellular portion of cleaved CDCP1) lead to increased LD abundance in primary tumors, decreased metastasis, and increased ACSL activity in two animal models of TNBC.

  3. These results revealed that ADAM9 (show ADAM9 Antibodies) down-regulates miR-1 (show FSD1 Antibodies) via activating EGFR (show EGFR Antibodies) signaling pathways, which in turn enhances CDCP1 expression to promote lung cancer progression.

  4. CDCP1 is a novel marker of the most aggressive N-positive triple-negative breast cancers; CDCP1 expression and gains in CDCP1 copy number synergized with nodal (N) status in determining disease-free and distant disease-free survival

  5. High expression level of CDCP1 is associated with recurrence in glioblastoma.

  6. These studies have important implications for the development of a therapeutic to block CDCP1 activity and Triple-negative breast cancer (TNBC)metastasis.

  7. CDCP1 may facilitate loss of adhesion by promoting activation of EGFR (show EGFR Antibodies) and Src (show SRC Antibodies) at sites of cell-cell and cell-substratum contact.

  8. Stromal expression patterns for both ADAM12 (show ADAM12 Antibodies) and CDCP1.

  9. these data demonstrated that HIF-2alpha (show EPAS1 Antibodies) could promote hepatocellular carcinoma cell migration by regulating CDCP1

  10. Our results establish that differential glycosylation, cell surface presentation and extracellular expression of CDCP1 are hallmarks of prostate cancer progression.

Mouse (Murine) CUB Domain Containing Protein 1 (CDCP1) interaction partners

  1. Results indicate Cdcp1 (CD318) as a ligand of T-cell differentiation antigen CD6 (CD6 (show CD6 Antibodies)) and a potential target for the diagnosis and treatment of autoimmune diseases.

  2. Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor (show RYK Antibodies) cross-talk in unanchored cells.

  3. established mechanism for initiation of CDCP1-mediated signaling; demonstrated that processing of surface CDCP1 by extracellular serine proteases is prerequisite for CDCP1-dependent survival of cancer cells during metastasis; preventing cleavage of CDCP1 abrogated survival signaling associated with CDCP1 and induced PARP1 (show PARP1 Antibodies) cleavage and PARP1 (show PARP1 Antibodies)-mediated apoptosis

  4. CDCP1 may have a role in neoplasm metastasis; targeting it with a monoclonal antibody inhibits metastasis in a prostate cancer model

CUB Domain Containing Protein 1 (CDCP1) Antigen Profile

Protein Summary

The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with CDCP1

  • CUB domain containing protein 1 (CDCP1) antibody
  • CUB domain containing protein 1 (Cdcp1) antibody
  • CUB domain containing protein 1a (cdcp1a) antibody
  • 9030022E12Rik antibody
  • AA409659 antibody
  • CD318 antibody
  • E030027H19Rik antibody
  • RGD1305578 antibody
  • SIMA135 antibody
  • TRASK antibody
  • zgc:113071 antibody

Protein level used designations for CDCP1

CUB domain-containing protein 1 , membrane glycoprotein gp140 , subtractive immunization M plus HEp3-associated 135 kDa protein , transmembrane and associated with src kinases

GENE ID SPECIES
64866 Homo sapiens
109332 Mus musculus
484797 Canis lupus familiaris
301082 Rattus norvegicus
420703 Gallus gallus
100065703 Equus caballus
739085 Pan troglodytes
100450442 Pongo abelii
541520 Danio rerio
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