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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Antibodies

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Additionally we are shipping Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Kits (38) and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins (35) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CEACAM1 634 P13688
CEACAM1 81613 P16573
CEACAM1 26365 P31809
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Top anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Antibodies at antibodies-online.com

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IF/ICC Flow cytometric analysis of mouse SEMA4D (CD100) expression on splenocytes. 100 μL 14 to 16 Days
$312.53
Details
Human Mouse Un-conjugated EIA, FACS, IHC (fro), IF Fig. 1: Specificity testing of GM8G5. BOSC cells were transiently transfected with expression vectors containing the cDNA of either CEACAM1, 3, 4, 5, 6, 7 or 8. Expression of the constructs was tested with monoclonal antibodies known to recognise the corresponding proteins (B, coloured curves, D14HD11, BAC2, 80H3), an irrelevant monoclonal antibody served as negative control (red curves). For specificity testing (A), GM8G5 hybridoma supernatant was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM1 transfected cells (purple curve). Fig. 2: GM8G5 on renal cell carcinoma (RCC). Hybridoma supernatant of GM8G5 recognises CEACAM1 expressed on the surface of native RCC (orange curve) and on RCC stimulated with IFN (red curve). PBS served as negative control (black curve). 0.1 mg 6 to 8 Days
$445.50
Details
Human Mouse Un-conjugated cELISA, FACS, IHC (fro) Specificity testing of GM8G5. BOSC cells were transiently transfected with expression vectors containing the cDNA of either CEACAM1, 3, 4, 5, 6, 7 or 8. Expression of the constructs was tested with monoclonal antibodies known to recognise the correspondi GM8G5 on renal cell carcinoma (RCC). Hybridoma supernatant of GM8G5 recognises CEACAM1 expressed on the surface of native RCC (orange curve) and on RCC stimulated with IFN-gamma (red curve). PBS served as negative control (black curve) 100 μg 6 to 7 Days
$466.13
Details
Human Mouse Un-conjugated IHC (p), WB Anti-CEA antibody (monoclonal), IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-CEA antibody (monoclonal), IHC(P) IHC(P): Human Rectal Cancer Tissue 100 μg 4 to 6 Days
$280.00
Details
Human Mouse Un-conjugated ELISA, ELISA (Detection), FACS, IHC (p) Immunochemical Staining of human CEACAM1 in human colon carcinoma with Mouse Monoclonal Antibody (15 µg/m, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of epithelial cells. Immunochemical Staining of human CEACAM1 in human liver with Mouse Monoclonal Antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to bile canaliculus. The left panel: tissue incubated with primary antibody; The 100 μL 14 to 16 Days
$352.65
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Rat Liver Tissue. 100 μg 15 to 18 Days
$380.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-CEACAM1 antibody ABIN1048423 IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD66a expression in A549 (A), HT29 (B), SW620 (C), mouse liver (D), mouse kidney (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CD66 (Phospho-Ser508) using Calc LOVO whole cell lysates 100 μL 11 to 12 Days
$450.00
Details
Human Mouse FITC FACS Flow cytometric analysis of Human CEACAM1(CD66a) expression in HT29 cells. 100 Tests 14 to 16 Days
$236.18
Details

Top referenced anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Antibodies

  1. Human Monoclonal CEACAM1 Primary Antibody for EIA, FACS - ABIN114594 : Hammarström: The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. in Seminars in cancer biology 1999 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN4897487 : Gebauer, Wicklein, Tachezy, Grob, Steinemann, Manukjan, Göhring, Schlegelberger, Maar, Izbicki, Bockhorn, Schumacher: Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis. in Anticancer research 2016 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN2689373 : Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: Molecular cloning of nonspecific cross-reacting antigens in human granulocytes. in The Journal of biological chemistry 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN2689374 : Siler, Eggensperger, Hand, Milenic, Miller, Houchens, Hinkle, Schlom: Therapeutic efficacy of a high-affinity anticarcinoembryonic antigen monoclonal antibody (COL-1). in Biotechnology therapeutics 1994 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CEACAM1 Primary Antibody for IHC (p), WB - ABIN3043635 : Li, Chen, Zeng, Li, Zhang, Lin, Zhang, Xie, He, Shu, Yang, Tang, Fu: Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. in Experimental cell research 2015 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal CEACAM1 Primary Antibody for CyTOF, FACS - ABIN4900284 : Rahmoun, Molès, Pedretti, Mathieu, Fremaux, Raison-Peyron, Lecron, Yssel, Pène: Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. in The Journal of investigative dermatology 2009 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CEACAM1 Primary Antibody for FACS - ABIN4897486 : Samineni, Zhang, Shively: Carcinoembryonic antigen-related cell adhesion molecule 1 negatively regulates granulocyte colony-stimulating factor production by breast tumor-associated macrophages that mediate tumor angiogenesis. in International journal of cancer 2013 (PubMed)

  8. Human Monoclonal CEACAM1 Primary Antibody for IHC (p), ELISA - ABIN513717 : Nichita, Zurac, Bastian, Stinga, Nedelcu, Brinzea, Turcu, Ion, Jilaveanu, Sticlaru, Popp, Cioplea: Comparative analysis of CEACAM1 expression in thin melanomas with and without regression. in Oncology letters 2019 (PubMed)

More Antibodies against Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Interaction Partners

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. After knockdown of CEACAM1 tube formation of human dermal lymphatic endothelial cells (HDLECs) was increased with elevated transcription factor Prox1 expression, suggesting that CEACAM1 downregulates Prox1 and plays an inhibitory role in tube formation of HDLECs.

  2. Together, these findings demonstrate that the outcome of gonococcal infection is determined by both the cell type-specific expression of human CEACAM1 and CEACAM5 and their specificity for the bacterial Opa variants expressed, which combine to determine the level of gonococcal association with the genital mucosa versus the extent of CEACAM-dependent inflammation and gonococcal clearance by neutrophils.

  3. CEACAM1 overexpression in TSCC promoted tumor formation and growth.

  4. IRF1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately regulate CEACAM1 transcription, alternative splicing, and translation and may significantly contribute to CEACAM1 silencing in cancer.

  5. Study concludes that CEACAM1 is an important regulator of virus-specific CD8+ T cell functions in mice and humans and represents a promising therapeutic target for modulating CD8+ T cells.

  6. regulator of local immune response in the liver, whereby CEACAM1S seems to control regulatory T cell induction

  7. These experiments also confirmed that protein levels of CEACAM-1, which functions in cell adhesion, is dependent on LLO biosynthesis in vivo. Kato III cells and the MPDU1-rescued Kato IIIM cells therefore provide a novel model to examine the consequences of defective LLO biosynthesis both in vitro and in vivo.

  8. The MAPK-driven CEACAM1p activity is mediated by ETS1.

  9. CEACAM1 mRNA or protein expression are independent prognostic markers for ovarian cancer carcinomas.

  10. We suggest that CEACAM1 could be a prognostic marker of oral squamous cell carcinoma and oral carcinoma in situ. Our most important finding was that it could help pathologists diagnosing oral carcinoma in situ

  11. GNAS mutation is a highly specific test for IPMN. When GNAS testing is added to CEA and KRAS, a significantly greater overall accuracy (86.2%) is achieved.

  12. CEACAM1 single nucleotide polymorphisms association with lymphedema caused by Wuchereria bancrofti.

  13. HBx, VEGF and CEACAM1 were widely expressed in HBV-related HCC. HBx may facilitate occurrence and progression of HBV-related HCC via down-regulating CEACAM1 and up-regulating VEGF.

  14. these data identify CEACAM1 as a clinically highly interesting target in multiple sclerosis pathogenesis and open new therapeutic avenues for the treatment of the disease.

  15. serum levels of CEACAM1 in healthy pregnant women were much lower than in non-pregnant women

  16. CEACAM1 overexpression significantly suppressed MM cell proliferation, induced cell apoptosis, and inhibited cell invasion and migration possibly through activation of caspase-3 and downregulation of MMP-2 and MMP-9.

  17. Data suggest that the serum level of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) may be used to discriminate gastrointestinal cancer patients from health controls.

  18. In this paper, a dual-target electrochemical aptasensor has been developed for simultaneous detection of carcinoembryonic antigen and mucin-1 based on metal ion electrochemical labels and Ru(NH3)6(3+) electronic wires

  19. Furthermore, the proposed aptasensor was successfully applied in determining CEA in serum samples, showing its superior prospects in clinical diagnosis.

  20. we show here that Human Metapneumovirus (HMPV)-infected cells upregulates CEACAM1 to restrict HMPV infection

Mouse (Murine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. CEACAM1 negatively regulates RP105 signaling in monocytes by recruitment of SHP-1, resulting in the sequestration of pVAV1 and beta-actin from RP105. This novel pathway and regulation of IL-6 signaling by CEACAM1 defines a novel role for monocytes in the fever response of mice to LPS

  2. Study using NLRC5 deficient mice found that NLRC5 exacerbated renal injury by the development of postischemic renal inflammation and the induction of tubular epithelial cell apoptosis that was associated with, at least in part, the negative regulation of CEACAM1. This suggests that NLRC5 signaling in renal parenchymal cells plays the dominant role in mediating renal damage.

  3. In this study, a CEACAM-1 overexpression vector was constructed, and the effects of CC1 overexpression post CVB3 infection were analyzed. The results suggested that CC1 may promote CAR expression in cardiomyocytes after CVB3 infection, and CAR may be a potential target for CC1 to regulate the CVB3-induced process of myocardial injury. CC1 might regulate CAR expression by activating the CC1-SYK- TNF-[alpha] signaling axis.

  4. these results identify a crucial role for CEACAM1 in endothelial homeostasis of adult blood vessels.

  5. Liver-specific rescuing of Ceacam1 reversed endothelial and cardiac dysfunction in Cc1-/-liver+ mice.

  6. Study concludes that CEACAM1 is an important regulator of virus-specific CD8+ T cell functions in mice and humans and represents a promising therapeutic target for modulating CD8+ T cells.

  7. regulator of local immune response in the liver, whereby CEACAM1S seems to control regulatory T cell induction

  8. CEACAM1 controls epithelial-mesenchymal transition in vitro and in vivo by site-specific regulation of beta-catenin phosphorylation

  9. A 30-day high fat feeding regimen demonstrated that white adipose tissue-derived fatty acids repressed hepatic CEACAM1-dependent regulation of insulin and lipid metabolism in 3-month-old male C57BL/6J mice.

  10. determined the crystal structure of mCEACAM1b and identified the structural differences and additional residue differences between mCEACAM1a and mCEACAM1b that affect MHV binding and entry

  11. REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation

  12. CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.

  13. The increase in total fat mass in Cc1(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin neurons in the arcuate nucleus is unclear, leptin resistance and elevated hypothalamic fatty-acid synthase activity could underlie altered energy balance in these mice.

  14. Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.

  15. hepatic CEACAM1 expression at fasting is mediated by Pparalpha-dependent mechanisms.

  16. Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.

  17. CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses

  18. High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.

  19. Ceacam1L acts as a crucial factor in glioblastoma-initiating cell maintenance and tumorigenesis by activating c-Src/STAT3 signaling. Monomers of the cytoplasmic domain of Ceacam1L bound to c-Src and STAT3 and induced their phosphorylation.

  20. CEACAM1 levels in the liver were reduced in prenatally stressed diet-induced obesity offspring after the high fat diet challenge, suggesting that preexisting genetic predisposition combined with prenatal stress increases the risk for obesity in adulthood.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Antigen Profile

Protein Summary

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Gene names and symbols associated with CEACAM1

  • carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM1) antibody
  • carcinoembryonic antigen-related cell adhesion molecule 1 (ceacam1) antibody
  • carcinoembryonic antigen related cell adhesion molecule 1 (Ceacam1) antibody
  • carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) antibody
  • carcinoembryonic antigen-related cell adhesion molecule 6 (LOC101103343) antibody
  • bb-1 antibody
  • Bgp antibody
  • Bgp1 antibody
  • BGPI antibody
  • BGPR antibody
  • C-CAM antibody
  • Cc1 antibody
  • Ccam1 antibody
  • CD66a antibody
  • Cea-1 antibody
  • Cea-7 antibody
  • Cea1 antibody
  • Cea7 antibody
  • CEACAM1 antibody
  • hm:zeh0068 antibody
  • Hv-2 antibody
  • Hv2 antibody
  • mCEA1 antibody
  • Mhv-1 antibody
  • MHVR antibody
  • MHVR1 antibody
  • mmCGM1 antibody
  • mmCGM1a antibody
  • mmCGM2 antibody
  • zeh0068 antibody

Protein level used designations for CEACAM1

CD66a antigen , antigen CD66 , carcinoembryonic antigen-related cell adhesion molecule 1 , ATP-dependent taurocolate-carrier protein , C-CAM 105 , CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin) , GP110 , bone gamma-carboxyglutamic acid (Gla) protein , cell-CAM 105 , ecto-ATPase , osteocalcin , pp120 , pp120/ecto-ATPase , BGP-1 , CEA-related cell adhesion molecule 1 , MHV-R , biliary glycoprotein 1 , biliary glycoprotein D , carcinoembryonic antigen 1 , carcinoembryonic antigen 7 , hepatitis virus (MHV-4) susceptibility , hepatitis virus receptor , murine hepatitis virus receptor , carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) , carcinoembryonic antigen-related cell adhesion molecule 6

GENE ID SPECIES
634 Homo sapiens
114465 Danio rerio
612435 Canis lupus familiaris
81613 Rattus norvegicus
26365 Mus musculus
101103343 Ovis aries
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