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CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR1 Kits (32) and CCR1 Proteins (9) and many more products for this protein.
Showing 10 out of 201 products:
Human Monoclonal CCR1 Primary Antibody for FACS - ABIN4898192
Broux, Mizee, Vanheusden, van der Pol, van Horssen, Van Wijmeersch, Somers, de Vries, Stinissen, Hellings: IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis. in Journal of immunology (Baltimore, Md. : 1950) 2015
Show all 19 Pubmed References
Human Monoclonal CCR1 Primary Antibody for CyTOF, FACS - ABIN4900686
Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 16 Pubmed References
Human Polyclonal CCR1 Primary Antibody for FACS, ICC - ABIN4288916
Demoule, Divangahi, Danialou, Gvozdic, Larkin, Bao, Petrof: Expression and regulation of CC class chemokines in the dystrophic (mdx) diaphragm. in American journal of respiratory cell and molecular biology 2005
Show all 6 Pubmed References
Mouse (Murine) Monoclonal CCR1 Primary Antibody for CyTOF, FACS - ABIN4899318
Baba, Naka, Morishita, Komatsu, Hirao, Mukaida: MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia. in The Journal of experimental medicine 2013
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Human Monoclonal CCR1 Primary Antibody for FACS - ABIN4898187
de la Rica, García-Gómez, Comet, Rodríguez-Ubreva, Ciudad, Vento-Tormo, Company, Álvarez-Errico, García, Gómez-Vaquero, Ballestar: NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. in Genome biology 2015
Mouse (Murine) Monoclonal CCR1 Primary Antibody for FACS - ABIN4895916
Fleming, Chandrasekaran, Dillon, Dalby, Suresh, Sarkar, El-Sayed, Mosser: The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. in Journal of leukocyte biology 2015
Mouse (Murine) Monoclonal CCR1 Primary Antibody for FACS - ABIN4895914
Sun, Chen, Lin, Chen, Yu, Hou, Li: Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain. in Molecular immunology 2016
Human Polyclonal CCR1 Primary Antibody for IHC, IHC (p) - ABIN4288932
Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. in Journal of immunology (Baltimore, Md. : 1950) 2009
Mouse (Murine) Polyclonal CCR1 Primary Antibody for ELISA - ABIN4258851
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
Results reveal that CCR1 expression is positively correlated with OPN (show SPP1 Antibodies) expression in hepatocellular carcinoma cells, and the patients with high levels of both OPN (show SPP1 Antibodies) and CCR1 have the most dismal prognosis. Study also, shows that steopontin upregulates CCR1 in HCC (show FAM126A Antibodies) cells and, that CCR1 is essential for osteopontin (show SPP1 Antibodies)-induced HCC (show FAM126A Antibodies) metastasis.
Expression of CCR1 was measured in retrospective clinical specimens of colorectal cancer lung metastases. CCR1+ cells accumulated around the CCL15 (show CCL15 Antibodies)-positive colorectal cancer cells in the lung, but few around the CCL15 (show CCL15 Antibodies)-negative ones.
during renal transplantation, CD4+ and CD8+ T cells expressing CCR1 were increased in patients who developed renal allograft dysfunction
MIP-1alpha (show CCL3 Antibodies) receptor antagonism can significantly reduce T cell migration to the secreted factors from Oesophagogastric adenocarcinoma omentum and liver.
These data suggest that CCR1/CCR2B (show CCR2 Antibodies) could be involved in clearing EBV-infected latency III B cells in immunocompetent individuals via directing the migration of these cells and attracting the chemokines-expressing immune cells.
Data suggest that the interplay between CCR1 upregulation and inactivation of CXCR4 (show CXCR4 Antibodies) signaling (the CCR1/CXCR4 (show CXCR4 Antibodies) axis) drives the egress of multiple myeloma PCs from the bone marrow, leading to disease dissemination.
Basophil migration into skin lesions of Systemic Lupus Erythematosus patients were observed, but not in normal skin tissue. This migration was related to the upregulation of chemokine receptors CCR1 and CCR2 on basophils.
Study indicates that two distinct micro-environmental factors, CD40L (show CD40LG Antibodies) and Mphis, signal via CCR1 to induce AKT (show AKT1 Antibodies) activation resulting in translational stabilization of MCL-1 (show MCL1 Antibodies), and hence can contribute to CLL cell survival.
CCL15 activation of CCR1 plays critical roles in hepatocellular carcinoma metastasis.
CCL15-positive primary colorectal cancers recruited approximately 2.2 times more numbers of CCR1(+) cells.
The enhanced presence of CCL3 can explain the immediate analgesic effects, independent from an anti-inflammatory action, evoked by the administration of the CCR1 antagonist J113863 in carrageenan- and complete Freund's adjuvant inflamed mice.
Inhibition of CCR1, the distal part of this signaling relay, may have a therapeutic impact in metastatic disease with lower toxicity than blocking upstream targets.
Data indicate that deletion or inhibition of CC chemokine receptor 1 (CCR1) decreases pain responses.
CCR1-mediated accumulation of myeloid cells in the liver microenvironment promotes mouse colon cancer metastasis.
CCR1 is required for recruitment of neutrophils during respiratory infection with modified vaccinia virus Ankara.
This study demonstrates a Tpl2 (show MAP3K8 Antibodies)-dependent mechanism for macrophage expression of select chemokine (show CCL1 Antibodies) receptors.
Ccr1 plays a critical role in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of NZB/W mice, which in turn contribute to the progression of renal injury.
CCR1.beta-arrestin-2 (show ARRB2 Antibodies) complex may be related to a potential scavenging function of the receptor, which may be important for maintenance of chemokine (show CCL1 Antibodies) gradients and receptor responsiveness in complex fields of chemokines during inflammation.
CCR1 expression by both hematopoietic and nonhematopoietic cells favors tumor aggressiveness and liver cancer metastasis development.
findings show that CCR1 is pivotal for bone remodeling induced by mechanical loading during orthodontic tooth movement and these actions depend, at least in part, on CCL3 (show CCL3 Antibodies)
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
, C-C chemokine receptor type 1
, LD78 receptor
, RANTES receptor
, macrophage inflammatory protein 1-alpha receptor
, MIP-1 alpha R
, MIP-1 alphaR
, chemokine (C-C) receptor 1
, macrophage inflammatory protein-1 alpha receptor
, chemokine receptor