anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Antibodies

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Additionally we are shipping Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CSTF2T 83410 Q8C7E9
CSTF2T 23283 Q9H0L4
CSTF2T 309338  
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Top anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB WB Suggested Anti-CSTF2T Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human brain Sample Type :  SKOV3   Primary Antibody Dilution:  4 ug/ml   Secondary Antibody :  Anti-rabbit Alexa 546   Secondary Antibody Dilution:  2 ug/ml   Gene Name :  CSTF2T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CSTF2T Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/MCF-7 cells, using CSTF2T Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from MCF-7 cells using CSTF2T antibody.,The lane on the left is treated with the antigen-specific peptide. ABIN6275019 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using CSTF2T antibody (ABIN1875955) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s. 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated WB Western Blot analysis of CSTF2T expression in transfected 293T cell line by CSTF2T MaxPab polyclonal antibody.Lane 1: CSTF2T transfected lysate(67.76 KDa).Lane 2: Non-transfected lysate. CSTF2T MaxPab polyclonal antibody. Western Blot analysis of CSTF2T expression in rat brain. 50 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using CSTF2T antibody (ABIN5972585) at 1/1000 dilution. 100 μL Log in to see 11 to 16 Days
$412.19
Details

More Antibodies against Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Interaction Partners

Mouse (Murine) Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) interaction partners

  1. Cstf2t may control other reproductive functions that are not directly linked to the formation of 3' ends of mature polyadenylated mRNAs during male germ cell formation.

  2. Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice

  3. This demonstrates that tauCstF-64 is an important stage-specific regulator of Crem mRNA processing that modulates the spatial and temporal expression of downstream stage-specific genes necessary for the proper development of sperm in mice.

  4. The results suggest that tauCstF-64 plays a role in 3' end determination and transcription termination for a large range of germ cell-expressed genes.

  5. primarily supports spermatogenesis, but only incidently supports immune cell function

  6. tauCstF-64 is required not only for expression of genes involved in morphological differentiation of spermatids but also for genes having products that function during interaction of motile spermatozoa with eggs.

  7. physiologically increased levels of CstF-64 observed in LPS-stimulated RAW macrophages contribute to the changes in expression and alternative polyadenylation of a number of genes

  8. These results suggest the hypothesis that tauCstF-64 mRNA is regulated at the translational or post-translational level.

  9. tauCstF-64 promotes germ-cell-specific patterns of polyadenylation by binding to different downstream sequence elements.

  10. Targeted disruption of Cstf2t in mice causes aberrant spermatogenesis, specifically disrupting meiotic and postmeiotic development, resulting in male infertility resembling oligoasthenoteratozoospermia.

  11. The Cstf2t protein contributes to proteomic diversity by regulating alternative polyadenylation of neural mRNAs.

Human Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) interaction partners

  1. CSTF2tau binds many previously not recognized RNAs including histone, snoRNA and snRNAs. CSTF2tau-binding is associated with internal oligoadenylation resulting in shortened snRNA isoforms subjected to rapid degradation. CSTF2tau controls the abundance of snRNAs resulting in alternative splicing of several RNAs with critical roles in tumorigenesis and cardiac function.

  2. CstF64 and CstF64tau modulate one another's expression and play overlapping as well as distinct roles in regulating global alternative polyadenylation profiles.

  3. Studied expression levels of CstF-64 in EV71-infected cells; showed reduction of CstF-64 during virus infection correlated with production of viral 3C(pro). CstF-64 was cleaved in vitro by 3C(pro) not by mutant 3C(pro) variants.

  4. Radiation hybrid mapping places the human tauCstF-64 gene at 10q22-q23, which is the site of a translocation that has been associated with human neurological problems and male infertility.

  5. structure of the RNA-binding domain of CstF-64 containing an RNA recognition motif (RRM) augmented by N- and C-terminal helices

  6. upstream element in human papillomavirus type 16 interacted specifically with CstF-64, hnRNP C1/C2 & polypyrimidine tract binding protein, suggesting these factors were enhancing or regulating polyadenylation at the HPV-16 early polyadenylation signal

Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Antigen Profile

Protein Summary

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs.

Gene names and symbols associated with CSTF2T

  • cleavage stimulation factor, 3' pre-RNA subunit 2, tau (Cstf2t) antibody
  • cleavage stimulation factor subunit 2 tau variant (CSTF2T) antibody
  • cleavage stimulation factor subunit 2, tau variant (Cstf2t) antibody
  • 64kDa antibody
  • C77975 antibody
  • CstF-64T antibody
  • tauCstF-64 antibody
  • tCstF-64 antibody

Protein level used designations for CSTF2T

CF-1 64 kDa subunit tau , CF-1 64 kDa subunit, tau , CSTF 64 kDa subunit tau , CSTF 64 kDa subunit, tau , cleavage stimulation factor 64 kDa subunit tau , cleavage stimulation factor 64 kDa subunit, tau , cleavage stimulation factor subunit 2 tau , cleavage stimulation factor subunit 2 tau variant , cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa, tau , tauCstF-64 , cleavage stimulation factor, 3' pre-RNA subunit 2, tau

GENE ID SPECIES
83410 Mus musculus
23283 Homo sapiens
783569 Bos taurus
309338 Rattus norvegicus
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