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Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.
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Cow (Bovine) Polyclonal CKMT2 Primary Antibody for IHC, WB - ABIN2776839
Guerrero, Wuyam, Mezin, Vivodtzev, Vendelin, Borel, Hacini, Chavanon, Imbeaud, Saks, Pison: Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise training in lung transplant skeletal muscle. in American journal of physiology. Regulatory, integrative and comparative physiology 2005
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These findings support increased CK activity as protection against ischaemia-reperfusion injury, in particular, protection via CKMT2 in a cardiac-relevant cell line, which merits further investigation in vivo.
three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components
After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase (show SLC25A5 Antibodies)-mitochondrial creatine kinase.
CK2alpha has a role in progression of acute myeloid leukemia (show BCL11A Antibodies)
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
sarcomeric mitochondrial creatine kinase
, Creatine kinase S-type, mitochondrial
, Creatine kinase, sarcomeric mitochondrial
, creatine kinase S-type, mitochondrial
, basic-type mitochondrial creatine kinase
, mitochondrial creatine kinase 2
, Basic-type mitochondrial creatine kinase