CKMT2 antibody (N-Term)

Catalog No. ABIN391093

Product Details anti-CKMT2 Antibody

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Binding Specificity: AA 56-86, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKMT2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This CKMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-86 amino acids from the N-terminal region of human CKMT2.

Clone: RB5383-5384

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CKMT2

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Alternative Name: CKMT2 (CKMT2 Products)

Synonyms: 2300008A19Rik antibody, ScCKmit antibody, MIBCK antibody, SMTCK antibody, ckmt2-2 antibody, zgc:73059 antibody, CKMT2 antibody, Mib-CK antibody, S-MtCK antibody, creatine kinase, mitochondrial 2 antibody, creatine kinase, mitochondrial 2 (sarcomeric) antibody, creatine kinase, mitochondrial 2b (sarcomeric) antibody, CKMT2 antibody, ckmt2 antibody, Ckmt2 antibody, ckmt2b antibody

Background: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.

Molecular Weight: 47504

Gene ID: 1160

NCBI Accession: NP_001093205, NP_001093206, NP_001816

UniProt: P17540