anti-Cyclin-Dependent Kinase 14 (CDK14) Antibodies

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Additionally we are shipping CDK14 Proteins (12) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDK14 5218 O94921
CDK14 18647 O35495
CDK14 362316  
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Top anti-CDK14 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-Cdk14 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PFTK1 / CDK14  Antibody in mouse liver tissue lysates (35ug/lane). PFTK1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PFTK1 Antibody [NBP1-80920] - Immunohistochemical staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: PFTK1 Antibody [NBP1-80920] Staining of human cell line U-2 OS shows positivity in nucleus & cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PFTK1 antibody (N-term) (ABIN391791) in mouse cerebellum tissue lysates (35 µg/lane). PFTK1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with PFTK1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PFTK1 Antibody (N-term P82) (ABIN390748) in mouse cerebellum tissue lysates (35 µg/lane). PFTK1 (arrow) was detected using the purified polyclonal antibody. PFTK1 Antibody (N-term P82) (ABIN390748) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) Formalin-fixed and paraffin-embedded human testis tissue reacted with PFTK1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PFTK1 Antibody (N-term P82) in mouse cerebellum tissue lysates (35ug/lane). PFTK1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of lysate from human brain tissue lysate, using PFTK1 Antibody (N-term P82) at 1:1000 at each lane. PFTK1 Antibody (N-term P82) (RB18842) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PFTK1 Antibody (N-term P82) for immunohistochemistry. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Mouse Rabbit Un-conjugated WB Western Blot: PFTK1 Antibody [NBP1-98270] - Mouse Pancreas Lysate 1.0ug/ml, Gel Concentration: 12% 100 μL Log in to see 8 to 11 Days
$485.88
Details

CDK14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CDK14 Antibodies

  1. Human Polyclonal CDK14 Primary Antibody for WB - ABIN1881191 : Quina, Wang, Ng, Turner: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CDK14 Primary Antibody for ICC, IF - ABIN4345007 : Miyagaki, Yamasaki, Miyata, Takahashi, Kurokawa, Nakajima, Takiguchi, Fujiwara, Ishii, Tanaka, Mori, Doki: Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma. in British journal of cancer 2012 (PubMed)

More Antibodies against CDK14 Interaction Partners

Human Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. CDK14 mediated miR (show MLXIP Antibodies)-1202 to exert its anti-tumor effects.

  2. CDK14 expression was closely associated with poor prognosis and overall survival of Osteosarcoma patients. miR (show MLXIP Antibodies)-216a inhibits CDK14 expression by binding to the 3'-untranslated region of CDK14.

  3. PFTK1 expression is significantly higher in CRC (show CALR Antibodies) tissues compared with matched adjacent noncancerous colorectal tissues. The associations between PFTK1 expression and clinicopathological characters, and PFTK1 expression and the OS rate following resection suggested that PFTK1 may represent a novel biomarker of poor prognosis in CRC (show CALR Antibodies)

  4. Results show that CDK14 and DYRK2 (show DYRK2 Antibodies) expression were inversely correlated in human breast cancer tissues and identified CDK14 as a target of DYRK2 (show DYRK2 Antibodies).

  5. miR (show MLXIP Antibodies)-455 inhibits breast cancer cell proliferation through targeting CDK14

  6. findings revealed an unrecognized role of Caprin-2 (show CAPRIN2 Antibodies) in facilitating LRP5 (show LRP5 Antibodies)/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14, Cyclin Y (show CCNY Antibodies), and LRP5 (show LRP5 Antibodies)/6.

  7. these results suggest that knockdown of PFTK1 inhibited the proliferation and invasion of colon cancer cells as well as the EMT (show ITK Antibodies) progress by suppressing the Sonic hedgehog (show SHH Antibodies) signaling pathway.

  8. we report that PFTK1 downregulation might inhibit the proliferation and invasion of NSCLC cells by suppressing the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  9. The expression level of PFTK1 was correlated with tumor grade, FIGO stage, lymph node metastasis of EOC patients as well as poor prognosis.

  10. Knockdown of PFTK1 inhibited the proliferation and invasion of pancreatic cancer cells as well as the EMT (show ITK Antibodies) progress by suppressing the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

Mouse (Murine) Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. Cigarette smoke down regulates CDK14 levels and impairs Wnt (show WNT2 Antibodies) signaling.

  2. may be a key regulator for thyrotropin-releasing hormone (TRH (show TRH Antibodies)) action in the cerebellum through the NO-cGMP pathway

CDK14 Antigen Profile

Protein Summary

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene names and symbols associated with CDK14

  • cyclin dependent kinase 14 (CDK14) antibody
  • cyclin-dependent kinase 14 (Cdk14) antibody
  • cyclin-dependent kinase 14 L homeolog (cdk14.L) antibody
  • mKIAA0834 antibody
  • pftaire1 antibody
  • pftk1 antibody

Protein level used designations for CDK14

PFTAIRE protein kinase 1 , cell division protein kinase 14 , hPFTAIRE1 , serine/threonine-protein kinase PFTAIRE-1 , Cell division protein kinase 14

GENE ID SPECIES
463522 Pan troglodytes
703442 Macaca mulatta
100137460 Papio anubis
100173505 Pongo abelii
5218 Homo sapiens
18647 Mus musculus
362316 Rattus norvegicus
100328634 Oryctolagus cuniculus
420546 Gallus gallus
475223 Canis lupus familiaris
100515962 Sus scrofa
784403 Bos taurus
101424147 Dasypus novemcinctus
100391008 Callithrix jacchus
444781 Xenopus laevis
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