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anti-Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antibodies

The protein encoded by CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Additionally we are shipping Cyclin-Dependent Kinase 2 Associated Protein 1 Proteins (12) and Cyclin-Dependent Kinase 2 Associated Protein 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDK2AP1 13445 O35207
CDK2AP1 8099 O14519
CDK2AP1 360804  
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Top anti-Cyclin-Dependent Kinase 2 Associated Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of CDK2AP1 expression in HUVEC (A), HeLa (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using CDKPA1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: DOC1 Antibody [NBP1-84064] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Western Blot: DOC1 Antibody [NBP1-84064] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human, Small Intestine: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 16 Days
$476.15
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ICC, WB   50 μg Log in to see 7 to 9 Days
$581.17
Details
Human Mouse Un-conjugated DB, ICC Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-CDK2AP1 antibody. Left: CDK2AP1 staining. Right: Coomassie Blue staining of immunized recombinant protein. 50 μg Log in to see 6 to 8 Days
$285.71
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

CDK2AP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , , , ,
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Rat (Rattus)


Top referenced anti-Cyclin-Dependent Kinase 2 Associated Protein 1 Antibodies

  1. Human Polyclonal CDK2AP1 Primary Antibody for IHC, IHC (p) - ABIN4305761 : Dieterich, Mellberg, Langenkamp, Zhang, Zieba, Salomäki, Teichert, Huang, Edqvist, Kraus, Augustin, Olofsson, Larsson, Söderberg, Molema, Pontén, Georgii-Hemming, Alafuzoff, Dimberg: Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization. in The Journal of pathology 2012 (PubMed)

More Antibodies against Cyclin-Dependent Kinase 2 Associated Protein 1 Interaction Partners

Mouse (Murine) Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) interaction partners

  1. Cdk2ap1 expression is primarily regulated by progesterone and the progesterone receptor (show PGR Antibodies) in uterus and is mainly localized to proliferating tissues.

  2. Results indicate that DOC-1 (show CA6 Antibodies) is a bona fide subunit of the Mi-2 (show CHD4 Antibodies)/NuRD chromatin remodeling complex.

  3. (CDK2 (show CDK2 Antibodies)-AP1 (show JUN Antibodies)) is a potential gene therapeutic agent for oral/head and neck cancer in conjunction with DNA-damaging agents such as cisplatin.

  4. p12CDK2-AP1 (show JUN Antibodies) forms nuclear homodimers in contact inhibited normal diploid cells and dimerization of p12 is a necessary process for the growth inhibition effect by p12

  5. Results suggest that overexpression of CDK2 (show CDK2 Antibodies)-associating protein 1 (p12CDK2AP1) leads to testicular and ovarian abnormalities, a phenotype closely related to that of cdk2 (show CDK2 Antibodies)-/- mice.

  6. Cdk2ap1, a negative regulator of Cdk2 (show CDK2 Antibodies) function and cell cycle, promotes Oct4 (show POU5F1 Antibodies) promoter methylation during murine embryonic stem cell differentiation to down-regulate Oct4 (show POU5F1 Antibodies) expression.

  7. Cdk2ap1 plays an essential role in the early stage of embryogenesis and has a potential role during craniofacial morphogenesis.

  8. CDK2AP1-mediated differentiation of murine embryonic stem cell was elicited through the regulation of pRb (show PGR Antibodies).

Human Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) interaction partners

  1. Knockdown of CDK2AP1 in hESCs results in increased p53 (show TP53 Antibodies) and enhances differentiation and favors it over a self-renewal fate.

  2. DOC1 re-expression in oral cancer cells causes a reversal of EMT (show ITK Antibodies). DOC1 promotes NURD binding to a subset of target loci.

  3. The simultaneous overexpression of p12CDK2-AP1 (show FOSB Antibodies) and CD82 (show CD82 Antibodies) significantly suppressed the in vivo tumor growth.

  4. knockdown of CDK2AP1 in primary human fibroblasts reduced proliferation and induced premature senescence, with the observed phenotype being p53 (show TP53 Antibodies) dependent

  5. In summary, p12CDK2AP1 expression in myxofibrosarcoma cells induces G0/G1 arrest and mitochondria dependent proapoptotic activity and down-regulation of p12CDK2AP1 by shRNAi results in up-regulation of the CDK2 (show CDK2 Antibodies) transcript and protein.

  6. Study reports that knockdown of CDK2AP1 by RNAi in glioma cells could effectively inhibit cell proliferation by inducing cell cycle arrest and apoptosis

  7. CDK2AP1 plays an important role in modulating the growth and tumorigenesis of lung cancer cells.

  8. Low CDK2AP1 expression is common and associated with adverse prognosis in nasopharyngeal carcinoma.

  9. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region

  10. In comparison with the healthy gingiva, the expression of Doc-1 was decreased, whereas the expression of S100A7 (show S100A7 Antibodies) was upregulated in all oral lesions.

Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antigen Profile

Protein Summary

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with CDK2AP1

  • cyclin-dependent kinase 2 associated protein 1 S homeolog (cdk2ap1.S) antibody
  • cyclin dependent kinase 2 associated protein 1 (CDK2AP1) antibody
  • cyclin dependent kinase 2 associated protein 1 pseudogene (LOC475806) antibody
  • cyclin-dependent kinase 2 associated protein 1 (cdk2ap1) antibody
  • CDK2 (cyclin-dependent kinase 2)-associated protein 1 (Cdk2ap1) antibody
  • cyclin-dependent kinase 2 associated protein 1 (Cdk2ap1) antibody
  • cyclin dependent kinase 2 associated protein 1 (Cdk2ap1) antibody
  • Apc10 antibody
  • Cdkap1 antibody
  • doc-1 antibody
  • DOC1 antibody
  • DORC1 antibody
  • MGC64532 antibody
  • p12 antibody
  • p12DOC-1 antibody
  • ST19 antibody

Protein level used designations for CDK2AP1

cyclin-dependent kinase 2 associated protein 1 , CDK2-associated protein 1 , CDK2 (cyclin-dependent kinase 2)-associated protein 1 , cyclin-dependent kinase 2-associated protein 1 , CDK2-associated protein1 , deleted in oral cancer 1 , putative oral cancer suppressor , Deleted in oral cancer-1

GENE ID SPECIES
380551 Xenopus laevis
452342 Pan troglodytes
475806 Canis lupus familiaris
549484 Xenopus (Silurana) tropicalis
615387 Bos taurus
704412 Macaca mulatta
100153712 Sus scrofa
13445 Mus musculus
8099 Homo sapiens
360804 Rattus norvegicus
101825251 Mesocricetus auratus
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