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CDK2AP1 Products

(Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

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The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].

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Featured CDK2AP1 Categories

CDK2AP1 Antibodies

High quality antibodies with extensive validation data.

CDK2AP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDK2AP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (3)
Cat. No. ABIN7445237
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, ICC, IF
Validations
  • (2)
Cat. No. ABIN6260725
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1327353
Quantity 50 μg
Datasheet Datasheet

Recommended CDK2AP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN427674
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1128266
Quantity 96 tests
Datasheet Datasheet

Recommended CDK2AP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348940
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3131468
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419961
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CDK2AP1 products

Dieterich, Mellberg, Langenkamp, Zhang, Zieba, Salomäki, Teichert, Huang, Edqvist, Kraus, Augustin, Olofsson, Larsson, Söderberg, Molema, Pontén, Georgii-Hemming, Alafuzoff, Dimberg: "Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization." in: The Journal of pathology, Vol. 228, Issue 3, pp. 378-90, (2012) (PubMed).

Synonyms and alternative names related to CDK2AP1

cyclin-dependent kinase 2 associated protein 1 S homeolog (cdk2ap1.S), cyclin dependent kinase 2 associated protein 1 (CDK2AP1), cyclin dependent kinase 2 associated protein 1 pseudogene (LOC475806), cyclin-dependent kinase 2 associated protein 1 (cdk2ap1), CDK2 (cyclin-dependent kinase 2)-associated protein 1 (Cdk2ap1), cyclin-dependent kinase 2 associated protein 1 (Cdk2ap1), cyclin dependent kinase 2 associated protein 1 (Cdk2ap1), Apc10, Cdkap1, doc-1, doc1, Doc1, DOC1, dorc1, DORC1, MGC64532, p12, p12doc-1, p12DOC-1, st19, ST19

Protein level used designations for CDK2AP1

  • cyclin-dependent kinase 2 associated protein 1
  • CDK2-associated protein 1
  • CDK2 (cyclin-dependent kinase 2)-associated protein 1
  • cyclin-dependent kinase 2-associated protein 1
  • CDK2-associated protein1
  • deleted in oral cancer 1
  • putative oral cancer suppressor
  • Deleted in oral cancer-1
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