anti-Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) Antibodies

The protein encoded by FCGR3B is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). Additionally we are shipping FCGR3B Kits (32) and FCGR3B Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FCGR3B 2215 O75015
FCGR3B    
FCGR3B    
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Top anti-FCGR3B Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Mouse Un-conjugated IHC (p) Immunochemical staining of human CD16b(a&b) in human lung with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated ICC, IHC, WB 100 μg 13 to 16 Days
$332.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of lysate from HL-60 cell line, using FCGR3B Antibody at 1:1000. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using FCGR3B antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Mouse FITC FACS   100 Tests 6 to 8 Days
$654.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD16b expression in Jurkat (A), THP1 (B), mouse liver (C), mouse thymus (D), rat spleen (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD16b expression in Jurkat (A), THP1 (B), mouse liver (C), mouse thymus (D), rat spleen (E) whole cell lysates. 100 μL 11 to 18 Days
$383.76
Details
Human Mouse Un-conjugated ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using CD16B mAb against human CD16B (AA: 17-200) recombinant protein. (Expected MW is 46.8 kDa) 0.1 mg 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using FCGR3B antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using FCGR3B antibody. 200 μL 12 to 14 Days
$438.90
Details

Top referenced anti-FCGR3B Antibodies

  1. Human Monoclonal FCGR3B Primary Antibody for CyTOF, FACS - ABIN269010 : Gasdaska, Sherwood, Regan, Dickey: An afucosylated anti-CD20 monoclonal antibody with greater antibody-dependent cellular cytotoxicity and B-cell depletion and lower complement-dependent cytotoxicity than rituximab. in Molecular immunology 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal FCGR3B Primary Antibody for CyTOF, FACS - ABIN4899478 : Chauhan, Moore, Bi, Chen: FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression. in The Journal of biological chemistry 2016 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal FCGR3B Primary Antibody for FACS - ABIN2478780 : Ravetch, Kinet: Fc receptors. in Annual review of immunology 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal FCGR3B Primary Antibody for CyTOF, FACS - ABIN4899480 : Bergin, Reeves, Meleady, Henry, McElvaney, Carroll, Condron, Chotirmall, Clynes, ONeill, McElvaney: ?-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8. in The Journal of clinical investigation 2010 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal FCGR3B Primary Antibody for FACS - ABIN536111 : de Haas, Koene, Kleijer, de Vries, Simsek, van Tol, Roos, von dem Borne: A triallelic Fc gamma receptor type IIIA polymorphism influences the binding of human IgG by NK cell Fc gamma RIIIa. in Journal of immunology (Baltimore, Md. : 1950) 1996 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal FCGR3B Primary Antibody for FACS - ABIN536114 : Tamm, Schmidt: The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding. in Journal of immunology (Baltimore, Md. : 1950) 1996 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal FCGR3B Primary Antibody for FACS - ABIN536117 : Arase, Arase, Hirano, Yokosuka, Sakurai, Saito: IgE-mediated activation of NK cells through Fc gamma RIII. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal FCGR3B Primary Antibody for ELISA, FACS - ABIN4310943 : Wu, Tommasi di Vignano, Zhou, Michel-Dziunycz, Bai, Mi, Qin, Zu, Hofbauer: The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin. in PLoS genetics 2018 (PubMed)

More Antibodies against FCGR3B Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) interaction partners

  1. Study data confirm FcgammaRIIIb as a negative regulator of neutrophil antibody-dependent cellular cytotoxicity toward tumor cells and a potential target for enhancing tumor cell destruction by neutrophils.

  2. Collectively, these results indicate that the amino acid substitution Ala78Asp resulting in the HNA-1c allotype leads to higher affinity toward human IgG, enhancement of neutrophil activation, and possibly effective clearance of malaria by intracellular reactive oxygen species.

  3. SHP-2 is activated by CD16b crosslinking in neutrophils.

  4. FCGR3B deficiency due to copy number variations may predispose to eosinophilic granulomatosis with polyangiitis.

  5. low copy numbers of FCGR2A and FCGR3B to be common risk factors for systemic lupus nephritis (SLE) and ANCA-associated systemic vasculitis (AASV).

  6. The FCGR3B NA1/NA1 genotype is associated with hypersensitivity reactions to adalimumab in Japanese patients with Rheumatoid Arthritis.

  7. Data suggest association of FCGR3B deletion with increased risk of rheumatoid arthritis (RA) in a large cohort.

  8. Gene copy number variation (CNV) of the PKLR, FCGR2A, FCGR2C, and FCGR3 genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.

  9. Association between Fc gamma Receptor IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

  10. We conclude that FCGR3A CNVs are a major risk factor for female sarcoidosis and FCGR3B CNVs may also affect the development of sarcoidosis.

  11. CD16 and CD35 are important for neutrophil internalization of M. tuberculosis, whereas HIV-1 infection adversely affects opsonophagocytosis.

  12. There was no aberration in FCGR3B allele/genotype frequencies in sarcoidosis patients compared to controls.

  13. Results showed that susceptibility to systemic lupus erythematosus was associated with the FCGR3B*01 allele, as well as with the FCGR3B*01/*01 and FCGR3B*01/*02 genotypes.

  14. FcgammaRIIIB allelic distribution was similar among pediatric Guillain-Barre syndrome patients and controls.

  15. Lower copy numbers (

  16. This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.

  17. data show that cross-linking FcgammaRIIIb is responsible for NET formation by the human neutrophil

  18. our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.

  19. Fc-gamma receptor polymorphisms differentially influence susceptibility to systemic lupus erythematosus and lupus nephritis.

  20. the results of this meta-analysis indicated that low FCGR3B CN increased susceptibility to autoimmune diseases--{REVIEW}

FCGR3B Antigen Profile

Protein Summary

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Gene names and symbols associated with FCGR3B

  • Fc fragment of IgG receptor IIIb (FCGR3B) antibody
  • CD16 antibody
  • CD16b antibody
  • FCG3 antibody
  • FCGR3 antibody
  • FCR-10 antibody
  • FCRIII antibody
  • FCRIIIb antibody

Protein level used designations for FCGR3B

Fc fragment of IgG, low affinity IIIb, receptor for (CD16) , Fc-gamma receptor IIIb (CD 16) , fc-gamma RIII , fc-gamma RIII-beta , fc-gamma RIIIb , igG Fc receptor III-1 , low affinity immunoglobulin gamma Fc region receptor III-B

GENE ID SPECIES
2215 Homo sapiens
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