FCGR3B antibody (AA 18-125)

Catalog No. ABIN7158551

This Rabbit Polyclonal antibody specifically detects FCGR3B in IF and ELISA. It exhibits reactivity toward Human.

Quick Overview for FCGR3B antibody (AA 18-125) (ABIN7158551)

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCGR3B antibody is un-conjugated

Application: Immunofluorescence (IF), ELISA

Product Details anti-FCGR3B Antibody

Binding Specificity: AA 18-125

Purpose: FCGR3B Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B protein (18-125AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FCGR3B

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Alternative Name: FCGR3B

Background:

Background: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Aliases: CD16 antibody, CD16b antibody, CD16b antigen antibody, Fc fragment of IgG low affinity IIIb receptor antibody, Fc gamma receptor IIIb antibody, Fc gamma RIII antibody, Fc gamma RIII beta antibody, Fc gamma RIIIb antibody, Fc-gamma RIII antibody, Fc-gamma RIII-beta antibody, Fc-gamma RIIIb antibody, FCG3 antibody, FCG3B_HUMAN antibody, FCGR3 antibody, FCGR3B antibody, FcR 10 antibody, FcR-10 antibody, FcR10 antibody, FcRIII antibody, FcRIIIb antibody, IGFR3 antibody, IgG Fc receptor III 1 antibody, IgG Fc receptor III-1 antibody, Low affinity immunoglobulin gamma Fc region receptor III B antibody, Low affinity immunoglobulin gamma Fc region receptor III-B antibody

UniProt: O75015