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FUS Proteins

(Fused in Sarcoma (FUS))

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].

recommended

FUS Protein (AA 287-376) (His-IF2DI Tag) (ABIN7123020)

FUS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

FUS Protein (AA 1-526) (Strep Tag) (ABIN3080272)

Crystallography grade FUS Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB

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recommended

FUS Protein (AA 1-518) (Strep Tag) (ABIN3120534)

Crystallography grade FUS Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB

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FUS Proteins by Grade

Find FUS Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

FUS Proteins by Origin

Find FUS Proteins for a variety of species such as anti-Human FUS, anti-Canine Distemper Virus (CDV) FUS, anti-Human respiratory syncytial virus A FUS. The species listed below are among those available. Click on a link to go to the corresponding products.

FUS Proteins by Source

Here you will find FUS Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FUS Proteins by Protein Type

Here you can find FUS Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

FUS Proteins by Application

Find FUS Proteins validated for a specific application such as SDS, ELISA, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FUS Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FUS Protein (AA 287-376) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123020

Quantity 50 μg

Datasheet Datasheet

FUS Protein (AA 1-526) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3080272

Quantity 1 mg

Datasheet Datasheet

FUS Protein (AA 1-518) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3120534

Quantity 1 mg

Datasheet Datasheet

FUS Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2721461

Quantity 20 μg

Datasheet Datasheet

FUS Protein (AA 137-574) (His tag)

Reactivity Human respiratory syncytial virus B

Source Yeast

Validations

Cat. No. ABIN5714278

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 27-529) (His tag)

Reactivity Human respiratory syncytial virus A

Source Yeast

Validations

Cat. No. ABIN5714158

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 136-608) (His-SUMO Tag)

Reactivity Canine Distemper Virus (CDV)

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5710740

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 1-198, partial) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1608021

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our FUS Proteins

Bogaert, Boeynaems, Kato, Guo, Caulfield, Steyaert, Scheveneels, Wilmans, Haeck, Hersmus, Schymkowitz, Rousseau, Shorter, Callaerts, Robberecht, Van Damme, Van Den Bosch: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).

Gorthi, Romero, Loranc, Cao, Lawrence, Goodale, Iniguez, Bernard, Masamsetti, Roston, Lawlor, Toretsky, Stegmaier, Lessnick, Chen, Bishop: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).

Blokhuis, Koppers, Groen, van den Heuvel, Dini Modigliani, Anink, Fumoto, van Diggelen, Snelting, Sodaar, Verheijen, Demmers, Veldink, Aronica, Bozzoni, den Hertog, van den Berg, Pasterkamp: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).

Altmeyer, Neelsen, Teloni, Pozdnyakova, Pellegrino, Grøfte, Rask, Streicher, Jungmichel, Nielsen, Lukas: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).

Groen, Fumoto, Blokhuis, Engelen-Lee, Zhou, van den Heuvel, Koppers, van Diggelen, van Heest, Demmers, Kirby, Shaw, Aronica, Spliet, Veldink, van den Berg, Pasterkamp: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).

Aliases for FUS Proteins

FUS RNA binding protein (FUS) Proteins
fused in sarcoma (Fus) Proteins
FUS RNA binding protein (Fus) Proteins
fused in sarcoma (FUS) Proteins
ALS6 Proteins
D430004D17Rik Proteins
D930039C12Rik Proteins
ETM4 Proteins
FUS/TLS Proteins
FUS1 Proteins
Fus1 Proteins
HNRNPP2 Proteins
POMP75 Proteins
TLS Proteins
Tls Proteins

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FUS Proteins by Grade

FUS Proteins by Origin

FUS Proteins by Source

FUS Proteins by Protein Type

FUS Proteins by Application

Popular FUS Proteins

Latest Publications for our FUS Proteins

Aliases for FUS Proteins

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