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The protein encoded by ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family.
Showing 10 out of 13 products:
Binding of NUFIP2 (show NUFIP2 Proteins) to Roquin (show RC3H1 Proteins) promotes recognition and regulation of ICOS mRNA.
Data show that inducible T cell co-stimulator (ICOS) deficient mice have a significant increase in the population of IL-17 (show IL17A Proteins)-producing Vgamma2+ gammadelta T cells in the thymus, spleen, lymph nodes and skin and exhibit exacerbated sensitization responses to 2,4-dinitrofluorobenzene.
Our results indicate that ICOS regulates the ontogeny and homeostasis of B6.Sle1 lupus prone mouse T follicular helper (TFH) cells and influences the function of TFH cells during aberrant germinal center B cell responses
The expression of ICOSL (show ICOSLG Proteins) in the cornea and the ICOS-mediated induction of Foxp3 (show FOXP3 Proteins)+ CD4 (show CD4 Proteins)+ regulatory T cells may contribute to successful corneal allograft survival.
this study reveals a previously unknown ICOS-TBK1 (show TBK1 Proteins) signaling pathway that specifies the commitment of germinal center follicular helper T cells
IFNAR1 (show IFNAR1 Proteins)-deficiency accelerated humoral immune responses and parasite control by boosting ICOS-signalling in two non-lethal murine models of malaria
Fecal levels of Crp1 (show CRIP1 Proteins) were significantly decreased in mice with graft-versus-host disease and were correlated with intestinal flora diversity.
IL-10 (show IL10 Proteins) production by CD4 (show CD4 Proteins)(+) YFP(+) T cells is controlled systemically during malaria infection through IL-27 (show IL27 Proteins) receptor signaling that is supported after CD4 (show CD4 Proteins)(+) T cell priming by ICOS signaling.
these data suggest ICOS is not required for follicular Th cell induction during Plasmodium chabaudi chabaudi AS infection
the ICOS signaling has a regulatory effect on CD154 (show CD40LG Proteins)/CD40 (show CD40 Proteins) expressions, and may play an important role in the hepatic egg granuloma formation of schistosomiasis.
we have found an association between chronic spontaneous urticaria and polymorphisms in the ICOS (show CTLA4 Proteins) gene. To our knowledge, this report is the fi rst (show SLC22A12 Proteins) to suggest and initially indicate a possible association of the ICOS (show CTLA4 Proteins) rs6726035 TT genotype with CSU pathogenesis.
Suggest that genetic polymorphisms of ICOS (show CTLA4 Proteins) function as sex-dependent risk factors for development of acute rejection in an Iranian kidney transplant population.
Binding of NUFIP2 (show NUFIP2 Proteins) to Roquin (show RC3H1 Proteins) promotes recognition and regulation of ICOS (show CTLA4 Proteins) mRNA.
OX40 (show TNFRSF4 Proteins) and ICOS (show CTLA4 Proteins) act in a cooperative, nonredundant manner to maximize and prolong the T follicular helper cell response that is generated after acute virus infection
High ICOS (show CTLA4 Proteins) expression is associated with colorectal neoplasms.
This is the first replication association study of rs4325730 upstream of ICOS (show CTLA4 Proteins) with AIH in the Japanese population and rs4325730G is a risk allele.
the induction pathway of ICOS (show CTLA4 Proteins)(+) Foxp3 (show FOXP3 Proteins)(+) cells was analyzed
ratio of ICOS (show CTLA4 Proteins)(+) /PD-1 (show PDCD1 Proteins)(+) Tfh cells and the frequency of IL-21 (show IL17C Proteins)(+) Tfh cells may be indicators for evaluating the idiopathic membranous nephropathy development
The ICOS (show CTLA4 Proteins) and ICOSL (show ICOSLG Proteins) SNPs examined do not have an apparent effect on the disease susceptibility and prognosis of autoimmune thyroid diseases.
Follicular helper T cells differentiation is a multistage process involving BCL6 (show BCL6 Proteins) and other transcription factors, cytokines, and costimulation through ICOS (show CTLA4 Proteins) and several other molecules. (Review)
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
inducible T-cell costimulator
, inducible T-cell co-stimulator
, CD28 and CTLA-4-like protein
, CD28-related protein 1
, activation-inducible lymphocyte immunomediatory molecule
, inducible costimulator