ICOS Protein (Cys137Ser-Mutant, Cys138Ser-Mutant) (His tag)
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- Target See all ICOS Proteins
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Protein Type
- Recombinant
- Protein Characteristics
- Cys137Ser-Mutant, Cys138Ser-Mutant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ICOS protein is labelled with His tag.
- Purpose
- Mouse ICOS/CD278 (C137S, C138S) Protein
- Sequence
- Glu21-Leu144 (C137S, C138S)
- Characteristics
- Recombinant Mouse ICOS/CD278(C137S, C138S) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Leu144(C137S, C138S).
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ICOS Protein
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Inducible T-Cell Co-Stimulator (ICOS) (AA 21-144) protein (Fc Tag)
ICOS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-141) protein (Fc Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-134) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys136Ser-Mutant), (Cys137Ser-Mutant) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rhesus Monkey Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Inducible T-Cell Co-Stimulator (ICOS) (AA 1-168) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) protein (mFc-His Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (His tag)Crystallography grade ICOS Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Alternative Name
- ICOS (ICOS Products)
- Synonyms
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Background
- Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1.
- Molecular Weight
- 15.3 kDa. Due to glycosylation, the protein migrates to 27-38 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9WVS0
- Pathways
- Cancer Immune Checkpoints
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