ICOS Protein (AA 21-144) (Fc Tag)
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- Target See all ICOS Proteins
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-144
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ICOS protein is labelled with Fc Tag.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ICOS Protein
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Inducible T-Cell Co-Stimulator (ICOS) (AA 21-144) protein (Fc Tag)
ICOS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-141) protein (Fc Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-134) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys136Ser-Mutant), (Cys137Ser-Mutant) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys137Ser-Mutant), (Cys138Ser-Mutant) protein (His tag)ICOS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rhesus Monkey Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Inducible T-Cell Co-Stimulator (ICOS) (AA 1-168) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) protein (mFc-His Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Alternative Name
- ICOS (ICOS Products)
- Synonyms
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Background
- Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Molecular Weight
- 40.6 kDa
- Pathways
- Cancer Immune Checkpoints
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