anti-Insulin-Degrading Enzyme Antibodies

IDE encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and k.

Data Quality
  • 1
  • 33
Type
  • 130
    Primary antibodies
Antigen
  • 130
Reactivity
  • 122
  • 54
  • 50
  • 5
  • 3
Application
  • 97
  • 53
  • 46
  • 16
  • 14
Detection Method
  • 3
Host
  • 101
  • 20
  • 9
Clonality
  • 109
  • 21
Clone
  • 3
  • 2
  • 1
  • 1
Binding Specificity
  • 15
  • 10
  • 9
  • 9
  • 4
Conjugate
  • 71
  • 9
  • 6
  • 5
  • 4
Isotype
  • 81
  • 3
  • 2
Format
  • 96
  • 3
130 Products
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN723680
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman
Application IF/ICC, IHC, IP, WB
Order details Cat. No. ABIN2934883
$422.09
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN334425
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityMouse (Murine), Rat (Rattus), Human
Application IHC, WB
Order details Cat. No. ABIN3022285
$523.93
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, FACS, IHC (p), WB
Order details Cat. No. ABIN5708390
$452.38
100 μg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Mouse, Monoclonal (3H4), IgG1
ReactivityHuman
Application WB
Order details Cat. No. ABIN3181153
$369.83
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF/ICC, IHC, WB
Order details Cat. No. ABIN6043556
$379.88
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IHC, WB
Order details Cat. No. ABIN6262443
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN544069
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IC, IF, IHC, WB
Order details Cat. No. ABIN3198139
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, ELISA, WB
Order details Cat. No. ABIN2428257
$493.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC (p), WB
Order details Cat. No. ABIN5534405
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityMouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN190754
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application ELISA, IHC, WB
Order details Cat. No. ABIN5539736
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN6391377
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN927297
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2854501
$466.18
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN561416
$305.71
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application IF/ICC, WB
Order details Cat. No. ABIN2990022
$422.09
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine)
Application IF, WB
Order details Cat. No. ABIN6568815
$438.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN2421703
$493.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN615842
$511.50
50 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN356957
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN2998075
$640.17
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
Mouse, Monoclonal (3H4), IgG1
ReactivityHuman
Application WB
Order details Cat. No. ABIN6288846
$309.14
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2143830
$483.57
50 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN1859248
$232.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2779367
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine)
Application IF, WB
Order details Cat. No. ABIN6714984
$390.55
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC, WB
Order details Cat. No. ABIN5902014
$422.09
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
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Insulin-Degrading Enzyme (IDE) Antigen Profile

Protein Summary

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

Gene names and symbols associated with IDE

  • insulin degrading enzyme (IDE) antibody
  • insulin-degrading enzyme (ide) antibody
  • insulin-degrading enzyme (LOC591315) antibody
  • insulin-degrading enzyme (CC1G_01115) antibody
  • insulin-degrading enzyme (Bm1_26615) antibody
  • insulin-degrading enzyme (PTRG_10875) antibody
  • metallopeptidase (SJAG_01430) antibody
  • insulin-degrading enzyme (EBI_21700) antibody
  • insulin-degrading enzyme (VDBG_06702) antibody
  • insulin-degrading enzyme (LOAG_08082) antibody
  • insulin-degrading enzyme (PGTG_04982) antibody
  • insulin-degrading enzyme (Tsp_00424) antibody
  • insulin degrading enzyme (Ide) antibody
  • 1300012G03Rik antibody
  • 4833415K22Rik antibody
  • AA675336 antibody
  • AI507533 antibody
  • IDE antibody
  • INSDEGM antibody
  • INSULYSIN antibody
  • zgc:162603 antibody

Protein level used designations for IDE

insulysin , insulin-degrading enzyme , insulin-degrading enzyme-like , insulin protease , insulinase , Abeta-degrading protease

GENE ID SPECIES
450608 Pan troglodytes
561390 Danio rerio
591315 Strongylocentrotus purpuratus
698640 Macaca mulatta
6009544 Coprinopsis cinerea okayama7130
6100223 Brugia malayi
6349187 Pyrenophora tritici-repentis Pt-1C-BFP
7051385 Schizosaccharomyces japonicus yFS275
8641122 Enterocytozoon bieneusi H348
9537184 Verticillium alfalfae VaMs.102
100071303 Equus caballus
100385143 Callithrix jacchus
100434053 Pongo abelii
100482236 Ailuropoda melanoleuca
9945508 Loa loa
10530847 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10901673 Trichinella spiralis
15925 Mus musculus
25700 Rattus norvegicus
3416 Homo sapiens
477768 Canis lupus familiaris
100341888 Oryctolagus cuniculus
100719651 Cavia porcellus
423814 Gallus gallus
100155309 Sus scrofa
523752 Bos taurus
101104194 Ovis aries
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