anti-Intercellular Adhesion Molecule 4 (ICAM4) Antibodies

ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. Additionally we are shipping ICAM4 Kits (13) and ICAM4 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ICAM4 3386 Q14773
ICAM4 78369 Q9ERM2
ICAM4 298702  
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Top anti-ICAM4 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human endometrial tissue labeled with Anti ICAM4 Polyclonal Antibody, Unconjugated (ABIN873300) at 1:200 followed by conjugation to the secondary antibody and DAB staining K562 lysates probed with ICAM4 Polyclonal Antibody, Uconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C. 100 μL 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Available
$363.46
Details
Human Goat Un-conjugated WB Staining of Human Umbillical Cord lysate using CD242 / ICAM4 Antibody  at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence 0.1 mg 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human Liver lysate; Primary Ab: 2µg/mL Rabbit Anti-Human ICAM4 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$332.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of ICAM4 transfected lysate using anti-ICAM4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with ICAM4 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of ICAM4 expression in transfected 293T cell line by ICAM4 MaxPab polyclonal antibody.Lane 1: ICAM4 transfected lysate(29.60 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using ICAM4 antibody. Western blot analysis of extracts of various cell lines, using ICAM4 antibody (ABIN4903997) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s. 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated WB Western Blot analysis of ICAM4 expression in transfected 293T cell line by ICAM4 MaxPab polyclonal antibody.Lane 1: ICAM4 transfected lysate(29.92 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg 11 to 14 Days
$610.50
Details

Top referenced anti-ICAM4 Antibodies

  1. Human Polyclonal ICAM4 Primary Antibody for WB - ABIN516775 : Zhu, Zennadi, Xu, Eu, Torok, Telen, McMahon: Impaired adenosine-5'-triphosphate release from red blood cells promotes their adhesion to endothelial cells: a mechanism of hypoxemia after transfusion. in Critical care medicine 2011 (PubMed)

  2. Human Polyclonal ICAM4 Primary Antibody for IF (p), IHC (p) - ABIN873300 : Polin, Pelc-Klopotowska, Danzer, Suessner, Gabriel, Wilflingseder, Żmudzin, Orzińska, Guz, Michalewska, Brojer: Compound heterozygosity of two novel RHAG alleles leads to a considerable disruption of the Rh complex. in Transfusion 2016 (PubMed)

  3. Human Polyclonal ICAM4 Primary Antibody for ELISA, WB - ABIN4320957 : Hermand, Le Pennec, Rouger, Cartron, Bailly: Characterization of the gene encoding the human LW blood group protein in LW+ and LW- phenotypes. in Blood 1996 (PubMed)

More Antibodies against ICAM4 Interaction Partners

Human Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. the effect of modulation of the cAMP-PKA-dependent pathway on ICAM-4 receptor activation

  2. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.

  3. ICAM-1 and ICAM-4 play roles in host cell invasion by M. tuberculosis and P. falciparum, respectively.

  4. Seven variant ICAM4 alleles were found, distinct from the wild-type ICAM4 allele (GenBank KF712272), known as LW*05 and encoding LW(a) .

  5. Data from differentiating cultured erythroid precursor cells suggest that RhAG (Rh-associated glycoprotein) knockdown abolishes Rh blood group expression (ICAM4; RhoD [ras homolog family member D]; CD47 Rh-related antigen) in erythroid cells.

  6. Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.

  7. In a transgenic mouse model of sickle cell disease ICAM-4 is implicated in abnormal adhesiveness of erythrocytes to endothelium.

  8. LWa allele occurs with incidence of 100% of donors in this study, while LWb allele has not been found in Chinese population.

  9. ICAM-4 as the first red blood cells protein ligand of platelets that may have relevant physiological significance

  10. binds to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins

  11. 12 single amino-acid changes in ICAM4 affected the interaction of ICAM-4 with alpha(V) integrins

  12. LW on sickle but not on normal erythrocytes undergoes increased PKA-dependent serine phosphorylation as a result of activation. The major counter receptor for LW was identified as the alphavbeta3 integrin on ECs

  13. Different integrins bind to different but partly overlapping sites on ICAM4, and ICAM4 may accommodate multiple integrin receptors present on leukocytes, platelets and endothelial cells.

  14. Review. LW antigen contributes to RBC adhesion, thrombosis, and (in sickle cell disease) vaso-occlusion.

  15. We show that ICAM-4 functions as a ligand for the monocyte/macrophage-specific CD11c/CD18. Deletion of the individual immunoglobulin domains of ICAM-4 demonstrated that both its domains contain binding sites for CD11c/CD18.

  16. LW play potentially pathophysiological roles in sickle cell disease

Mouse (Murine) Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. A novel second splice cDNA encodes an ICAM-4 isoform lacking the membrane-spanning domain. Erythroblasts express both isoforms. This new isoform, ICAM-4S, may modulate membrane-associated ICAM-4 binding & regulate erythroblast molecular attachments.

  2. ICAM-4 is critical in erythroblastic island formation via ICAM-4/alpha(V) adhesion

ICAM4 Antigen Profile

Protein Summary

This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100\; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ICAM4

  • intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4) antibody
  • intercellular adhesion molecule 4, Landsteiner-Wiener blood group (Icam4) antibody
  • intercellular adhesion molecule 4 (ICAM4) antibody
  • 1810015M19Rik antibody
  • Cd242 antibody
  • ICAM-4 antibody
  • LW antibody

Protein level used designations for ICAM4

CD242 antigen , LW blood group protein , Landsteiner-Wiener blood group antigen a , Landsteiner-Wiener blood group glycoprotein , intercellular adhesion molecule 4 , intercellular adhesion molecule 4 (LW blood group) , LW glycoprotein , Landsteiner-Wiener blood group protein , intercellular adhesion molecule 4, Landsteiner-Wiener blood group

GENE ID SPECIES
3386 Homo sapiens
78369 Mus musculus
455698 Pan troglodytes
514873 Bos taurus
611265 Canis lupus familiaris
100516594 Sus scrofa
298702 Rattus norvegicus
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