Interleukin 27 (IL27) ELISA Kits

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (168) and IL27 Proteins (36) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IL27 246778 Q8NEV9
IL27 365368  
IL27 246779 Q8K3I6
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Top IL27 ELISA Kits at

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 10pg/mL 15.6-1000 pg/mL Mouse IL-27 p28 PicoKine ELISA Kit standard curve 96 Tests 4 to 6 Days
Human 10pg/mL 156-10000 pg/mL Human IL-27 PicoKine ELISA Kit standard curve 96 Tests 4 to 6 Days
Rat 2.9 pg/mL 7.8 pg/mL - 500 pg/mL 96 Tests 13 to 16 Days
Rabbit 1.0 pg/mL 50-1000 pg/mL   96 Tests 15 to 18 Days
Guinea Pig 1.0 pg/mL 50-1000 pg/mL   96 Tests 15 to 18 Days
Sheep 9.375 pg/mL 15.63 pg/mL - 1000 pg/mL A typical standard curve 96 Tests 13 to 16 Days
Monkey 1.0 pg/mL 50-1000 pg/mL   96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
Dog 1.0 pg/mL 50-1000 pg/mL   96 Tests 15 to 18 Days
Human 8.1 pg/mL n/a   96 Tests 11 to 16 Days

Top referenced IL27 ELISA Kits

  1. Mouse (Murine) IL27 ELISA Kit for Sandwich ELISA - ABIN365240 : Le Texier, Thebault, Carvalho-Gaspar, Vignard, Merieau, Usal, Cuturi, Wood, Chiffoleau: Immunoregulatory function of IL-27 and TGF-?1 in cardiac allograft transplantation. in Transplantation 2012 (PubMed)

  2. Human IL27 ELISA Kit for Sandwich ELISA - ABIN1672802 : Larousserie, Bardel, Pflanz, Arnulf, Lome-Maldonado, Hermine, Brégeaud, Perennec, Brousse, Kastelein, Devergne: Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. in The American journal of pathology 2005 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) IL27 ELISA Kit for Sandwich ELISA - ABIN1672803 : Larousserie, Charlot, Bardel, Froger, Kastelein, Devergne: Differential effects of IL-27 on human B cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 4 Pubmed References

  4. Human IL27 ELISA Kit for Sandwich ELISA - ABIN414441 : Li, Zhang, Ge, Zhou, Qi, Ma, Xue, Zhou, Yang: Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia. in Human immunology 2012 (PubMed)

  5. Rat (Rattus) IL27 ELISA Kit for Sandwich ELISA - ABIN416127 : Gao, Pang, Zhang, Li, Tu, Zhang, Niu, Xiong, Xiao, Zhao, Gao, Wang: Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata. in Frontiers in pharmacology 2016 (PubMed)

More ELISA Kits for IL27 Interaction Partners

Human Interleukin 27 (IL27) interaction partners

  1. A role for IL-27 in modulating innate immune responses to bacterial infection.

  2. The IL-27 promoted the regulatory effects of Human mesenchymal stromal cells (hPMSCs) by enhancing the generation of CD4(+)IL-10(+)IFN-gamma(+) T cells from activated PBMC.

  3. IL-27 appears to have a dual role in GBS, with initial pro-inflammatory effects, followed by anti-inflammatory properties during recovery.

  4. IL-27 is part of the antiviral response by uterine cells against potential pathogens; effect of estradiol on IL-27 production and sensitivity by fibroblasts demonstrates a selective hormone action on individual cell types in the uterus and suggests that IL-27 may have differential effects during the menstrual cycle

  5. This work represents an advance in biomedical science because it excludes the rs153109 A/G (IL-27) SNP, but points to the value of the rs1929992 A/G (IL-33) SNP, in determining susceptibility to breast cancer, so that the latter SNP may be used as a marker to identify individuals at high risk for this disease.

  6. Study found no statistically significant difference between the studied groups regarding the IL-27p28 genotypes and revealed that TNF-alpha rs1800629 polymorphism is a potential genetic-susceptibility factor for hepatitis C virus related cirrhosis and hepatocellular carcinoma progression in Egyptian patients.

  7. In vitro IL-8 production by IL-27 and IL-37 pre-treated neutrophils and monocytes was significantly inhibited.

  8. A total of 885 septic patients and 1101 healthy controls were enrolled and genotyped for IL-27 genetic variants (rs153109/-964A > G and rs17855750/2905 T > G). Quantitative real-time PCR and enzyme-linked immunosorbent assays were performed to detect IL-27 expression and cytokine production. The effect of the rs153109 polymorphism on IL-27 promoter activity was evaluated using a luciferase reporter assay, and THP-1 cell a

  9. elevated IL-27 correlated well with bacterial sepsis among neonatal patients with bloodstream infections

  10. Impaired TLR-induced IL-27 secretion and augmented expression of antigen presentation molecules result in chronic T cell activation which may fuel T cell-mediated inflammation in type-2 diabetes.

  11. Serum levels of IL-27 were decreased in patients with Parkinson's disease compared to those in healthy subjects.

  12. Early-stage non-small cell lung cancer is characterized by high IL-27 expression in the lower airways.

  13. IL-27 production was elevated during Clostridium difficile infection in humans and mice. Infected WSX-1-/- mice experienced increased weight loss, enhanced colonic histology damage, less Clostridium difficile clearance, and decreased survival compared to wild-type controls during Clostridium difficile infection.

  14. In humans only heterodimeric IL-27 is present.

  15. the efficacy of IL-27 in inhibiting endotoxin tolerance in human THP-1 monocytes and PMA-THP-1 macrophages is affected by membrane-bound and soluble CD14 expression.

  16. SMM do not induce the production of TNF-alpha and other cytokines while inhibiting LPS-induced IL-27 production by inhibiting the classical NF-kappaB pathway.

  17. IL-27 serum levels were significantly differences in early onset and late onset severe preeclampsia than in gestation matched healthy pregnancies (p=0.0376, p=0.0085, respectively). Our results suggest IL-27 might be a useful biomarker for disease severity in preeclampsia.

  18. Over-expression of IL-17 and IL-27 are involved in the pathogenesis of liver damage in children with human cytomegalovrius infection.

  19. Interleukin-27 differentially regulates the expression of seven novel microRNAs.

  20. Patients with tuberculous pleural effusion have an about 26-fold higher chance of being IL-27 test-positive compared to patients with malignant pleural effusion. [meta-analysis]

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. IL-27 may break immune tolerance.

  2. IL30 plays an important role in regulating prostate cancer stem-like cell behavior and metastatic potential, therefore targeting this cytokine could hamper prostate cancer progression or recurrence

  3. IL-27Ra-deficient Tregs and STAT1-deficient Tregs were less efficient than WT Tregs in suppressing antitumor immunity in vivo. CD39 inhibition significantly abolished IL-27-induced suppressive activities of Tregs. Thus, IL-27 signaling in Tregs critically contributes to protumorigenic properties of Tregs via up-regulation of CD39.

  4. IL-27 is essential for the generation of IL-10-producing effector cells in primary infection by MHV68.

  5. IL-27 induces IL-10 production in CD4 T cells during mouse cytomegalovirus infection.

  6. data suggested that IL-27/IL-27R expression induced by Toxoplasma gondii infection may regulate mast cell-mediated immune response during acute ocular toxoplasmosis in mouse model

  7. IL-27 has a unique ability to directly act on hematopoietic stem cells and promote their expansion and differentiation into myeloid progenitors in hematologic neoplasms and malaria. (Review)

  8. Mechanistic studies have identified that hyperlipidemia induces IL-27 production in a TLR4-dependent manner, likely via downregulating LXR expression in dendritic cells. In this case, mice lacking IL-27 do not develop enhanced antibody responses.

  9. IFN-gamma induces IL-30 production which suppresses IFN-gamma mediated liver inflammation.

  10. IL-27 signaling in Foxp3(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system

  11. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  12. this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4(+) single positive thymocytes.

  13. TTP, encoded by Zfp36, degrades p28 to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  14. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1-like cells in celiac disease

  15. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  16. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin.

  17. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS injection compared with control specimens.

  18. these findings highlight critical roles for IFN-gamma and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

  19. IL-27-induced Sca-1(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes and Blimp1.

  20. found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Antigen Profile

Antigen Summary

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with Interleukin 27 (IL27) ELISA Kits

  • interleukin 27 (IL27) antibody
  • interleukin 27 (Il27) antibody
  • IL-27 antibody
  • IL-27A antibody
  • IL-27p28 antibody
  • IL27 antibody
  • IL27A antibody
  • IL27p28 antibody
  • Il30 antibody
  • p28 antibody
  • RGD1561420 antibody

Protein level used designations for Interleukin 27 (IL27) ELISA Kits

IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 , interleukin 27 p28 subunit , p28

246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
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