Interleukin 32 alpha Proteins (IL32A)

IL32A encodes a member of the cytokine family. Additionally we are shipping Interleukin 32 alpha Antibodies (17) and Interleukin 32 alpha Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL32A 9235 P24001
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Top Interleukin 32 alpha Proteins at antibodies-online.com

Showing 7 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$122.84
Details
Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 1 to 2 Days
$638.00
Details
Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$93.59
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$955.00
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$323.08
Details
Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 15 to 19 Days
$338.10
Details
Human Un-conjugated   1 mg Log in to see 6 to 8 Days
$3,283.50
Details

IL32A Proteins by Origin and Source

Origin Expressed in
Human

More Proteins for Interleukin 32 alpha (IL32A) Interaction Partners

Human Interleukin 32 alpha (IL32A) interaction partners

  1. The peritoneal fluid concentration of IL-32 was significantly higher in patients with advanced stage endometriosis compared with the controls.

  2. Studies indicate that some interleukin 32 (IL-32) isoforms have been linked to disease outcome and were shown to positively influence tumor development and progression in various different malignancies [Review].

  3. Interleukin 32 (IL-32) is important to limit the parasite dissemination from the site of infection [Review].

  4. IL-32gamma functions as intracellular effector in hepatocytes for suppressing hepatitis b virus replication.

  5. Results indicate that interleukin-32 gamma (IL-32gamma) plays a protective role for bone loss, providing clinical evidence of a negative correlation between IL-32gamma and DKK1 (Dickkopf-1) as bone metabolic markers.

  6. Our study shows a functional effect of a promoter single-nucleotide polymorphism (SNP) in IL32 on lipid profiles in RA patients and individuals, suggesting a possible protective role of this SNP against CVD.

  7. IL-32 may be an important pro-inflammatory molecule involved in calcific aortic valve disease.

  8. High IL32 expression is associated with hepatocellular carcinoma.

  9. Strong expression of IL-32 was detected in cardiomyocytes from heart failure patients.

  10. The increase in serum levels of IL-32 in accordance with additive effect of the presence of C allele in Multiple sclerosis patients might introduce IL-32 as a key player in MS pathogenesis or immunedysregulation

  11. Collectively, these results demonstrated that IL-32alpha upregulates the atheroprotective genes Timp3 and Reck by downregulating microRNA-205 through regulation of the Rprd2-Dgcr8/Ddx5-Dicer1 biogenesis pathway.

  12. high expression of both IL17A and IL32 leads to enhancement of T cell responses in breast tumors

  13. In transgenic mice, the presence of IL-32gamma contributes to the lesion healing caused by Leishmania braziliensis but not by Leishmania amazonensis.

  14. High IL32 expression is associated with lung metastasis in melanoma.

  15. In Kaposi sarcoma (KS) splicing ratio of the IL-32 isoforms showed IL-32gamma as the highest expressed isoform, followed by IL-32beta, in HIV-related KS cases compared with controls. Our data suggest a possible survival mechanism by the splicing of IL-32gamma to IL-32beta and also IL-6, IL-8, and CXCR1 signaling pathways to reverse the proapoptotic effect of the IL-32gamma isoform, leading to tumor cell survival and th...

  16. Three single nucleotide polymorphisms (SNPs) (rs28372698, rs12934561, rs4786370) of the IL32 gene have been proposed as modifiers for different diseases. The present study found no significant differences in the genotypic frequencies between the patients and healthy controls and no relation to survival for any of the SNPs.

  17. This study showed that the induction level of IL-32 was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS-induced IL-32 expression in nasal polyp-derived fibroblasts was regulated via the TLR4/JNK/AKT/CREB signaling pathway.

  18. findings show that IL-32alpha acts on NK cells to inhibit IL-15-mediated STAT5 phosphorylation and to suppress their IL-15-induced effector molecule expression and cytolytic capacity. IL-32alpha also acted on DCs by downregulating IL-15-induced IL-18 production, an important cytokine in NK cell activity.

  19. Thus, endogenous IL-32 is a crucial cytokine involved in the host defense against Leishmania parasites.

  20. Study indicated the overexpression of IL-32 in induced sputum of smokers and chronic obstructive pulmonary disease (COPD) patients, which was correlated with smoking exposure index and the degree of airway obstruction. It demonstrated that IL-32 might play critical role in smokers with COPD.

Interleukin 32 alpha (IL32A) Protein Profile

Protein Summary

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with Interleukin 32 alpha Proteins (IL32A)

  • interleukin 32 (IL32)
  • IL-32alpha protein
  • IL-32beta protein
  • IL-32delta protein
  • IL-32gamma protein
  • NK4 protein
  • TAIF protein
  • TAIFa protein
  • TAIFb protein
  • TAIFc protein
  • TAIFd protein

Protein level used designations for Interleukin 32 alpha Proteins (IL32A)

interleukin-32 , interleukin-32 eta , interleukin-32 small , interleukin-32 theta , natural killer cell transcript 4 , natural killer cells protein 4 , tumor necrosis factor alpha-inducing factor

GENE ID SPECIES
9235 Homo sapiens
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