Interleukin 32 alpha Proteins (IL32A)

IL32A encodes a member of the cytokine family. Additionally we are shipping Interleukin 32 alpha Kits (14) and Interleukin 32 alpha Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL32A 9235 P24001
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Top Interleukin 32 alpha Proteins at antibodies-online.com

Showing 5 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human Un-conjugated 100 μg 1 to 2 Days
$638.00
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg 2 to 3 Days
$955.00
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg 9 to 11 Days
$323.08
Details
Escherichia coli (E. coli) Human Un-conjugated   10 μg 15 to 19 Days
$338.10
Details
Human Un-conjugated   1 mg 6 to 8 Days
$3,283.50
Details

IL32A Proteins by Origin and Source

Origin Expressed in
Human

More Proteins for Interleukin 32 alpha (IL32A) Interaction Partners

Human Interleukin 32 alpha (IL32A) interaction partners

  1. Study using a human skin explant model demonstrated for the first time, that IL-32 is a molecular link between keratinocytes and Langerhans cells (LCs) in healthy skin, provoking LC migration from the epidermis to the dermis prior to their migration to the draining lymph nodes.

  2. Tumor associated fibroblast-secreted IL32 promotes breast cancer cell invasion and metastasis via integrin beta3-p38 MAPK signalling.

  3. Study shows that IL-32 mRNA and protein production was higher in rheumatoid arthritis patients compared to healthy individuals. Moreover, a slightly higher IL-32 expression was observed in patients bearing the CC-genotype for the IL-32 promoter SNP (rs4786370). These patients also tended to produce more pro-inflammatory cytokines in-vitro.

  4. rs4349147-G promotes transcription of non-IL-32alpha isoforms, generating a proinflammatory environment more conducive to HIV infection.

  5. IL32 blood levels are higher in latent tuberculosis patients than in patients with active tuberculosis.

  6. In Behcet's disease, IL-32 levels showed weak positive correlations with disease activity and were associated with certain disease manifestations, including articular symptoms.

  7. Regulation of IL-32 in human primary liver cells, HepG2 and THP-1cells strongly influences the mRNA expression of ABCA1, ABCG1, LXRalpha and apoA1 and affects intracellular lipid concentrations.

  8. The levels of IL-32, IL-1, and IFN-gamma protein and transcripts in serum and PBMCs from hepatitis B patients were higher than those in healthy volunteers.

  9. IL-32 is involved in fibrosis progression in the lungs

  10. Findings indicated that IL-32gamma suppressed skin carcinogenesis through the inhibition of both stemness and the inflammatory tumor microenvironment by the downregulation of TIMP-1 and ITGAV via inactivation of NF-kappaB signaling.

  11. The peritoneal fluid concentration of IL-32 was significantly higher in patients with advanced stage endometriosis compared with the controls.

  12. Studies indicate that some interleukin 32 (IL-32) isoforms have been linked to disease outcome and were shown to positively influence tumor development and progression in various different malignancies [Review].

  13. Interleukin 32 (IL-32) is important to limit the parasite dissemination from the site of infection [Review].

  14. IL-32gamma functions as intracellular effector in hepatocytes for suppressing hepatitis b virus replication.

  15. Results indicate that interleukin-32 gamma (IL-32gamma) plays a protective role for bone loss, providing clinical evidence of a negative correlation between IL-32gamma and DKK1 (Dickkopf-1) as bone metabolic markers.

  16. Our study shows a functional effect of a promoter single-nucleotide polymorphism (SNP) in IL32 on lipid profiles in RA patients and individuals, suggesting a possible protective role of this SNP against CVD.

  17. IL-32 may be an important pro-inflammatory molecule involved in calcific aortic valve disease.

  18. High IL32 expression is associated with hepatocellular carcinoma.

  19. Strong expression of IL-32 was detected in cardiomyocytes from heart failure patients.

  20. The increase in serum levels of IL-32 in accordance with additive effect of the presence of C allele in Multiple sclerosis patients might introduce IL-32 as a key player in MS pathogenesis or immunedysregulation

Interleukin 32 alpha (IL32A) Protein Profile

Protein Summary

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with Interleukin 32 alpha Proteins (IL32A)

  • interleukin 32 (IL32)
  • IL-32alpha protein
  • IL-32beta protein
  • IL-32delta protein
  • IL-32gamma protein
  • NK4 protein
  • TAIF protein
  • TAIFa protein
  • TAIFb protein
  • TAIFc protein
  • TAIFd protein

Protein level used designations for Interleukin 32 alpha Proteins (IL32A)

interleukin-32 , interleukin-32 eta , interleukin-32 small , interleukin-32 theta , natural killer cell transcript 4 , natural killer cells protein 4 , tumor necrosis factor alpha-inducing factor

GENE ID SPECIES
9235 Homo sapiens
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