anti-Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) Antibodies

LIPA encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase).

list all antibodies Gene Name GeneID UniProt
Anti-Human LIPA LIPA 3988 P38571
Anti-Rat LIPA LIPA 25055  
Anti-Mouse LIPA LIPA 16889 Q9Z0M5
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Top anti-Lipase A Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB 0.025 mL Log in to see 7 to 9 Days
$161.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LIPA AntibodyTitration: 1.0 µg/mL <br /> Positive Control: HepG2 Whole Cell <br /> LIPA is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Image Sample (50 ug of whole cell lysate) A: mouse Liver 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: A549 B: H1299 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB   100 μL Log in to see 10 to 11 Days
$428.57
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Liver tissue 100 μg Log in to see 15 to 18 Days
$360.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Liver tissue 100 μg Log in to see 15 to 18 Days
$380.00
Details
Human Mouse Un-conjugated IP, ELISA, WB Western Blot analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9.<br><br>Lane 1: LIPA transfected lysate(45 KDa).<br>Lane 2: Non-transfected lysate.<br> Detection limit for recombinant GST tagged LIPA is approximately 10ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9. Lane 1: LIPA transfected lysate(45 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged LIPA is approximately 10 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details

Top referenced anti-Lipase A Antibodies

  1. Human Monoclonal Lipase A Primary Antibody for ELISA, WB - ABIN969484 : Drebber, Andersen, Kasper, Lohse, Stolte, Dienes: Severe chronic diarrhea and weight loss in cholesteryl ester storage disease: a case report. in World journal of gastroenterology : WJG 2005 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Lipase A Primary Antibody for ELISA, WB - ABIN966473 : Boldrini, Devito, Biselli, Filocamo, Bosman: Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy. in Pathology, research and practice 2004 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Lipase A Primary Antibody for WB - ABIN517528 : Roszell, Tao, Yu, Huang, Bates: Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung. in American journal of physiology. Lung cellular and molecular physiology 2012 (PubMed)

  4. Human Polyclonal Lipase A Primary Antibody for ICC, IF - ABIN4331092 : Lettieri Barbato, Tatulli, Aquilano, Ciriolo: FoxO1 controls lysosomal acid lipase in adipocytes: implication of lipophagy during nutrient restriction and metformin treatment. in Cell death & disease 2013 (PubMed)

  5. Horse (Equine) Polyclonal Lipase A Primary Antibody for WB - ABIN611571 : Matsuoka, Huang, Elledge: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Lipase A Interaction Partners

Pig (Porcine) Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) interaction partners

  1. Cholesterol esterase shows enantioselective inhibition for enantiomers of exo (show PHM Antibodies)- and endo-2-norbornyl-N-n-butylcarbamates.

Human Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) interaction partners

  1. Report LIPA variants/phenotype in childhood-onset lysosomal acid lipase deficiency.

  2. LAL activity is significantly reduced in NAFLD (show TSC2 Antibodies), compared to that in HCV patients. This finding is particularly evident in the pre-cirrhotic stage of disease. LAL activity is also correlated with platelet and white blood cell count, suggesting an analytic interference of portal-hypertension-induced pancytopenia on DBS (show MCF2L Antibodies)-determined LAL activity.

  3. LAL plays a critical role in regulating mesenchymal stem cells' ability to stimulate tumor growth and metastasis, which provides a mechanistic basis for targeting LAL in MSCs to reduce the risk of cancer metastasis

  4. Report a marked reduction of LAL activity in patients with cryptogenic cirrhosis.

  5. LIPA mutations may have a role in with a clinical diagnosis of familial hypercholesterolemia

  6. Use CRISPR/Cas9 techniques to knockout LIPA in human induced pluripotent stem cells and differentiate them to macrophages.

  7. LIPA associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age /=160 mg/dl.

  8. Study demonstrates that liver cirrhosis from any etiology is characterized by a significant reduction of LAL activity but no known c.894G>A SNP, which is likely on an acquired base and independent from the etiology of hepatic disease.

  9. Coronary artery disease-associated coding variant rs1051338 causes reduced lysosomal LAL protein and activity because of increased LAL degradation.

  10. results indicate that LAL is the major acid RE hydrolase and required for functional retinoid homeostasis.

Mouse (Murine) Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) interaction partners

  1. LAL is critical for shuttling fatty acids derived from circulating lipoproteins to brown adipose tissue during cold exposure.

  2. Data show that lysosomal acid lipase (LAL)-deficient (-/-) macrophages accumulate neutral lipids, mainly cholesteryl esters, within lysosomes.

  3. Low LAL expression is associated with tumor growth and metastasis.

  4. The activity of lysosomal acid lipase was also decreased on treatment of macrophages with each modified LDL.

  5. results indicate that LAL is the major acid RE hydrolase and required for functional retinoid homeostasis.

  6. hLAL (show LIPF Antibodies) expression reduced tumor-promoting myeloid-derived suppressive cells in the liver of lal(-/-) mice

  7. Results indicate that LAL has a critical role in regulating MDSCs' ability to directly stimulate cancer cell proliferation and overcome immune rejection of cancer metastasis in allogeneic mice through modulation of the mTOR (show FRAP1 Antibodies) pathway.

  8. effect the loss of SOAT2 (show SOAT2 Antibodies) function has on tissue esterified cholesterol sequestration in lysosomal acid lipase-deficient mice in a model of cholesteryl ester storage disease

  9. Lipolysis of triacylglycerol substrates by LAL is important for M2 macrophage activation, and its inhibition suppresses M2 activation.

  10. LAL regulates endothelial cell function through interaction with myeloid-derived suppressor cells and modulation of the mTOR (show FRAP1 Antibodies) pathway, which provide mechanistic basis for targeting MDSCs or mTOR (show FRAP1 Antibodies) to rejuvenate EC functions in LAL deficiency-related diseases

Lipase A (LIPA) Antigen Profile

Protein Summary

This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with LIPA

  • lipase A, lysosomal acid type (LIPA) antibody
  • lipase A, lysosomal acid, cholesterol esterase (lipa) antibody
  • lipase A, lysosomal acid, cholesterol esterase (LIPA) antibody
  • lipase A, lysosomal acid, cholesterol esterase L homeolog (lipa.L) antibody
  • lipase A, lysosomal acid type (Lipa) antibody
  • lysosomal acid lipase A (Lipa) antibody
  • AA960673 antibody
  • CESD antibody
  • Chole antibody
  • Chole2 antibody
  • Lal antibody
  • Lip-1 antibody
  • Lip1 antibody
  • LIPA antibody

Protein level used designations for LIPA

lipase A, lysosomal acid, cholesterol esterase (Wolman disease) , lysosomal acid lipase/cholesteryl ester hydrolase , lipase A, lysosomal acid, cholesterol esterase , lysosomal acid lipase/cholesteryl ester hydrolase-like , acid cholesteryl ester hydrolase , cholesterol ester hydrolase , cholesteryl esterase , lysosomal acid lipase , sterol esterase , Cholesterol esterase (pancreatic) see D3Wox12 D3Wox13 D3Wox26 and D3Mgh25 , lysosomal acid lipase 1 , lysosomal acid lipase A , pancreatic cholesterol esterase , lipase A

GENE ID SPECIES
466150 Pan troglodytes
548564 Xenopus (Silurana) tropicalis
610650 Canis lupus familiaris
734759 Xenopus laevis
100071626 Equus caballus
100125267 Bos taurus
100142668 Sus scrofa
100145859 Ovis aries
100453604 Pongo abelii
100583764 Nomascus leucogenys
3988 Homo sapiens
25055 Rattus norvegicus
16889 Mus musculus
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