Lipase A antibody (N-Term)

Catalog No. ABIN2788678

The Rabbit Polyclonal anti-Lipase A antibody (ABIN2788678) specifically detects Lipase A in WB. The antibody is reactive with Human, Rat, Horse, Pig, Cow, Rabbit and Sheep samples.

Quick Overview for Lipase A antibody (N-Term) (ABIN2788678)

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reactivity: Human, Rat, Horse, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lipase A Antibody

Binding Specificity: N-Term

Purpose: LIPA Antibody - N-terminal region

Sequence: SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD

Predicted Reactivity: Cow: 93%, Horse: 86%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against LIPA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIPA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61109-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LIPA

Background:

Background Information: This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: Lipase A, lysosomal acid, cholesterol esterase

Alternative Symbols: LAL, CESD

Protein Name: Lysosomal acid lipase/cholesteryl ester hydrolase

Molecular Weight: 43kDa

Gene ID: 3988

NCBI Accession: NP_000226

UniProt: P38571