Lipase A antibody (AA 22-399)

Catalog No. ABIN7158764

Product Details anti-Lipase A Antibody

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Binding Specificity: AA 22-399

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase protein (22-399AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LIPA (LIPA Products)

Synonyms: cesd antibody, lal antibody, LIPA antibody, CESD antibody, LAL antibody, Chole antibody, Chole2 antibody, Lip1 antibody, AA960673 antibody, Lal antibody, Lip-1 antibody, lipase A, lysosomal acid type antibody, lipase A, lysosomal acid, cholesterol esterase antibody, lipase A, lysosomal acid, cholesterol esterase L homeolog antibody, lysosomal acid lipase A antibody, LIPA antibody, lipa antibody, lipa.L antibody, Lipa antibody

Background:

Background: Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.

Aliases: Acid cholesteryl ester hydrolase antibody, CESD antibody, cholesterol ester hydrolase antibody, cholesterol ester storage disease antibody, Cholesteryl esterase antibody, Hydrolase deficiency antibody, LAL antibody, LAL deficiency cholesterol ester antibody, LICH_HUMAN antibody, lipA antibody, LIPA deficiency antibody, Lipase A antibody, lipase A, lysosomal acid, cholesterol esterase antibody, lysosomal acid lipase antibody, lysosomal acid lipase deficiency antibody, Lysosomal acid lipase/cholesteryl ester hydrolase antibody, Sterol esterase antibody

UniProt: P38571