anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Antibodies

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MARCH5 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARCH5 54708 Q9NX47
MARCH5 69104 Q3KNM2
MARCH5 294079  
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Top anti-MARCH5 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: MARCH5 Sample Type: U937 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IC, IF, WB Western blot analysis of 42068 expression in HepG2 (A), mouse brain (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using MARCH5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of MARCH5 Antibody (N-term) (ABIN651864) in mouse kidney tissue lysates (35 µg/lane).MARCH5 (arrow) was detected using the purified polyclonal antibody. MARCH5 Antibody (N-term) (ABIN651864) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: MARCH5 Antibody [NBP2-21583] - Sample (20 ug of whole cell lysate) A: HeLa B: HeLa membrane, 12% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: MARCH5 Antibody [NBP2-21583] - Confocal immunofluorescence analysis of methanol-fixed HeLa, using 39145 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated WB Western Blot: MARCH5 Antibody [NBP1-59585] - COLO205 cells lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MARCH5 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details

MARCH5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MARCH5 Antibodies

  1. Cow (Bovine) Polyclonal MARCH5 Primary Antibody for WB - ABIN2774746 : Karbowski, Neutzner, Youle: The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. in The Journal of cell biology 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against MARCH5 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after Viral hemorrhagic septicemia virus infection.

Human Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. the results of this study identified MARCH5 as a candidate oncogene (show RAB1A Antibodies) in ovarian cancer and a potential target for ovarian cancer therapy.

  2. MARCH5 directly interacts with FUNDC1 (show FUNDC1 Antibodies) to mediate its ubiquitylation at lysine 119 for subsequent degradation.

  3. These findings and data showing MARCH5-dependent degradation of MiD49 (show SMCR7 Antibodies) upon stress support the possibility that MARCH5 regulation of MiD49 (show SMCR7 Antibodies) is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.

  4. Self-clearance mechanism of mitochondrial ligase MARCH5 contributes to mitochondria quality control.MARCH5 is regulated by auto-ubiquitination.

  5. MARCH5 binds MAVS (show MAVS Antibodies) only during viral stimulation when MAVS (show MAVS Antibodies) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (show MAVS Antibodies).

  6. Our results indicate that HDAC6 (show HDAC6 Antibodies) is a critical regulator of MFN2 (show MFN2 Antibodies) degradation by MARCH5, thus protecting mitochondrial connectivity from hypoxic stress.

  7. A fine balance of Mfn1 (show MFN1 Antibodies) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (show MFN1 Antibodies).

  8. MITOL regulates ER tethering to mitochondria by activating Mfn2 (show MFN2 Antibodies) via K192 ubiquitination.

  9. balance between LC1 (show MAP1B Antibodies) activation by S-nitrosylation and down-regulation by MITOL is critical for neuronal cell survival

  10. MARCH5 is an authentic E3 ubiquitin ligase (show MUL1 Antibodies) and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (show TLR7 Antibodies) signaling via releasing the inhibitory action of TANK toward TRAF6 (show TRAF6 Antibodies).

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. These findings suggest that MITOL plays a protective role against apoptosis in cardiomyocytes.

  2. MARCH5 binds MAVS (show MAVS Antibodies) only during viral stimulation when MAVS (show MAVS Antibodies) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (show MAVS Antibodies).

  3. March5 is involved in maintaining mouse-ESC (mESC) pluripotency via catalysis of Prkar1a (show PRKAR1A Antibodies) polyubiquitination and inhibition of the Raf (show RAF1 Antibodies)/MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) pathway.

  4. A fine balance of Mfn1 (show MFN1 Antibodies) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (show MFN1 Antibodies).

  5. MARCH5 is an authentic E3 ubiquitin ligase (show MUL1 Antibodies) and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (show TLR7 Antibodies) signaling via releasing the inhibitory action of TANK toward TRAF6 (show TRAF6 Antibodies).

  6. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

MARCH5 Antigen Profile

Protein Summary

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006

Gene names and symbols associated with MARCH5

  • membrane-associated ring finger (C3HC4) 5 (march5) antibody
  • membrane associated ring-CH-type finger 5 (MARCH5) antibody
  • membrane associated ring-CH-type finger 5 (march5) antibody
  • membrane associated ring-CH-type finger 5 L homeolog (march5.L) antibody
  • membrane-associated ring finger (C3HC4) 5 (March5) antibody
  • membrane associated ring-CH-type finger 5 (March5) antibody
  • 1810015H18Rik antibody
  • 2310008I22Rik antibody
  • 2700055A20Rik antibody
  • 5730499H23Rik antibody
  • E130202O05Rik antibody
  • Mar-05 antibody
  • MARCH-V antibody
  • MARCH5 antibody
  • Marchv antibody
  • MITOL antibody
  • Rnf153 antibody
  • zgc:162966 antibody

Protein level used designations for MARCH5

membrane-associated ring finger (C3HC4) 5 , E3 ubiquitin-protein ligase MARCH5 , MARCH-V , membrane-associated RING finger protein 5 , membrane-associated RING-CH protein V , mitochondrial ubiquitin ligase , ring finger protein 153

GENE ID SPECIES
100302643 Oncorhynchus mykiss
450607 Pan troglodytes
698517 Macaca mulatta
100144728 Xenopus (Silurana) tropicalis
100157340 Sus scrofa
100341637 Oryctolagus cuniculus
561952 Danio rerio
444564 Xenopus laevis
423815 Gallus gallus
54708 Homo sapiens
612766 Canis lupus familiaris
540937 Bos taurus
69104 Mus musculus
294079 Rattus norvegicus
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