MARCH5 antibody (N-Term)

Catalog No. ABIN651864

Product Details anti-MARCH5 Antibody

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Binding Specificity: AA 4-32, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, C, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MARCH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human MARCH5.

Clone: RB21862

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Alternative Name: MARCH5 (MARCH5 Products)

Synonyms: march5 antibody, MARCH5 antibody, mitol antibody, rnf153 antibody, march-v antibody, zgc:162966 antibody, MARCH-V antibody, Mar-05 antibody, MITOL antibody, RNF153 antibody, 1810015H18Rik antibody, 2310008I22Rik antibody, 2700055A20Rik antibody, 5730499H23Rik antibody, E130202O05Rik antibody, Marchv antibody, Rnf153 antibody, membrane-associated ring finger (C3HC4) 5 antibody, membrane associated ring-CH-type finger 5 antibody, membrane associated ring-CH-type finger 5 L homeolog antibody, march5 antibody, MARCH5 antibody, march5.L antibody, March5 antibody

Background: MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).

Molecular Weight: 31232

Gene ID: 54708

NCBI Accession: NP_060294

UniProt: Q9NX47