MARCH5 antibody

Catalog No. ABIN7116198

The Rabbit Polyclonal anti-MARCH5 antibody (ABIN7116198) specifically detects MARCH5 in ELISA, WB and IHC. The antibody is reactive with Human samples.

Quick Overview for MARCH5 antibody (ABIN7116198)

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MARCH5 Antibody

Purpose: MARCHF5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: membrane-associated ring finger(C3HC4) 5

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Alternative Name: MARCHF5

Background:

Synonyms: E3 ubiquitin-protein ligase MARCHF5|Membrane-associated RING finger protein 5|Membrane-associated RING-CH protein V (MARCH-V)|Mitochondrial ubiquitin ligase (MITOL)|RING finger protein 153|RING-type E3 ubiquitin transferase MARCHF5|MARCHF5|MARCH5|RNF153

Background: Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.

Molecular Weight: 31 kDa/65-70 kDa

Gene ID: 54708

UniProt: Q9NX47