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The protein encoded by NDUFA10 belongs to the complex I 42kDA subunit family.
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this study found specific loss of phosphorylation of serine-250 in complex I subunit NdufA10 due to PINK1 (show PINK1 Proteins) loss-of-function mutations that affect mitochondrial complex I activity.
NDUFA10 was found to be differentially methylated and expressed in human squamous cell carcinomas.
site of phosphorylation in NDUFA10 from bovine heart mitochondria by tandem mass spectrometry
The protein encoded by this gene belongs to the complex I 42kDA subunit family. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
, NADH:ubiquinone reductase 42kD subunit
, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
, OXPHOS complex I 42 kDa subunit
, NADH-ubiquinone oxidoreductase 42 kDa subunit
, complex I-42kD
, complex I 42kDa subunit