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NKRF encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. Additionally we are shipping NFKB Repressing Factor Antibodies (48) and NFKB Repressing Factor Proteins (7) and many more products for this protein.
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Human NKRF ELISA Kit for Sandwich ELISA - ABIN423153
Ventura, Vega, Chamorro, Aroca, Gómez, Pineda, Palacios, Blanca, Monteseirín: Allergen immunotherapy decreases LPS-induced NF-?B activation in neutrophils from allergic patients. in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2014
vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 ELISA Kits) and increasing PPARg (show PPARG ELISA Kits), GSTa (show GSTa2 ELISA Kits), and ABCA1 (show ABCA1 ELISA Kits) levels in aortae of rabbits fed a cholesterol-rich diet
MIR29 targets and reduces expression of CLDN1 (show CLDN1 ELISA Kits) and NKRF to increase intestinal permeability in inflammatory bowel disease.
The data of this study show that JKTBP1 and the 14-nt element act independently to mediate NRF internal ribosome entry segment activity.
NKRF is a nucleolar HSP essential for nucleolus homeostasis and cell survival under proteotoxic stress. NKRF is a thermosensor translocating from the nucleolus to the nucleoplasm during heat stress; nucleolar pools are replenished upon HSF1 (show HSF1 ELISA Kits)-mediated NKRF resynthesis. NKRF is an unconventional HSP crucial for correct rRNA processing. Under stress conditions, NKRF directs XRN2 (show XRN2 ELISA Kits) nucleolus/nucleoplasm trafficking.
Data suggest that L protein from LCMV interactions with host proteome, specifically DDX3X (show DDX3X ELISA Kits), NKRF, and TRIM21 (show TRIM21 ELISA Kits). (LCMV = Lymphocytic choriomeningitis mammarenavirus; DDX3X (show DDX3X ELISA Kits) = DEAD-box helicase 3; NKRF = NF-kappa-B-repressing factor; TRIM21 (show TRIM21 ELISA Kits) = tripartite motif-containing protein-21 (show TRIM21 ELISA Kits))
depletion of NKRF, XRN2 or DHX15 impairs an early pre-rRNA cleavage step.
NF-kappaB-repressing factor (NKRF) phosphorylation modulates promoter-proximal transcription elongation of NF-kappaB (show NFKB1 ELISA Kits)/NKRF-regulated genes via direct interactions with elongation complex in response to specific stimuli
The up-regulated NKRF serves as an endogenous repressor for IP-10 and IL-8 synthesis to hinder host from robust response to MTb infection.
NRF may serve as an endogenous repressor to prevent robust increase in IP-10/CXCL10 (show CXCL10 ELISA Kits) and IL-8/CXCL8 (show IL8 ELISA Kits) when TB bacterial load is high.
The expression of NKRF is decreased in PBMCs of patients with stable COPD (show ARCN1 ELISA Kits). The downregulation of NKRF was found to be closely related to enhanced IL-8 (show IL8 ELISA Kits) production from these peripheral blood cells through de-repression of the IL-8 (show IL8 ELISA Kits) promoter.
The results indicate that JKTBP1 regulates the level of NRF protein expression by binding to both NRF 5' and 3' UTRs.
role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene
GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
NFKB repressing factor
, transcription factor NRF
, NF-kappaB repressing factor
, nkrf (NF-kappaB repressing factor)
, NF-kappa-B-repressing factor-like
, NF-kappa-B-repressing factor
, NFkB-repressing factor