anti-PDZ Binding Kinase (PBK) Antibodies

PBKs encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family.

list all antibodies Gene Name GeneID UniProt
Anti-Human PBK PBK 55872 Q96KB5
Anti-Mouse PBK PBK 52033 Q9JJ78
Anti-Rat PBK PBK 290326  
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Top anti-PDZ Binding Kinase Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PBK Antibody Titration:  0.2-1 ug/ml  Positive Control:  721_B cell lysate PBK is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- PBK Picoband antibody, IHC(P) IHC(P): Mouse Testis Tissue Anti- PBK Picoband antibody, Western blotting All lanes: Anti PBK  at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: Mouse Testis Tissue Lysate at 50ug Lane 3: Human Placenta Tissue Lysate at 50ug Lane 4: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 36KD Observed bind size: 36KD 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: PBK Antibody [NBP1-84342] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: PBK Antibody [NBP1-84342] - Staining of mouse medulla shows positivity in a subset of cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of Hela cells using PBK mouse mAb (green) and negative control (red) . 100 μL Log in to see 2 to 3 Days
$430.10
Details
Human Rabbit Un-conjugated IHC, WB   200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells, treated with Nocodazole 1ug/ml 16h, using PBK/TOPK (Ab-9) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PBK/TOPK (Ab-9) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells treated with UV 30', using PBK/TOPK (Phospho-Thr9) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PBK (arrow) using rabbit polyclonal PBK Antibody (C-term C300) (ABIN391245).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PBK gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human testis tissue reacted with PBK Antibody (C-term C300) (ABIN391245), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, WB Immunohistochemistry: PBK Antibody (2C8) [NBP2-37514] - Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using PBK mouse mAb with DAB staining. ELISA: PBK Antibody (2C8) [NBP2-37514] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); 0.1 mL Log in to see 7 to 9 Days
$514.63
Details

Top referenced anti-PDZ Binding Kinase Antibodies

  1. Human Monoclonal PBK Primary Antibody for ICC, FACS - ABIN969345 : Oh, Zhu, Cho, Lee, Kang, Kim, Zykova, Bode, Dong: T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. in Cancer research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PBK Primary Antibody for WB - ABIN1881635 : Zykova, Zhu, Lu, Higgins, Tatsumi, Abe, Bode, Dong: Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PBK Primary Antibody for ICC, IF - ABIN4343992 : Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. in Molecular & cellular proteomics : MCP 2009 (PubMed)

More Antibodies against PDZ Binding Kinase Interaction Partners

Human PDZ Binding Kinase (PBK) interaction partners

  1. CDK1 (show CDK1 Antibodies)-mediated mitotic phosphorylation of PDZ-binding kinase is involved in cytokinesis and inhibits its oncogenic activity.

  2. Data suggest that T-LAK cell-originated protein kinase (TOPK) might play a pivotal role in breast cancer invasion and metastasis.

  3. our study provide convincing evidences that FoxM1 (show FOXM1 Antibodies)-regulated PBK exerts oncogenic activities towards HCC (show FAM126A Antibodies) via the activation of beta-Catenin (show CTNNB1 Antibodies) pathway.

  4. High TOPK expression is associated with liver cancer.

  5. The role of T-LAK cell-originated protein kinase directly promotes metastasis of colorectal cancer by modulating p53-related protein kinase (show TP53RK Antibodies).

  6. TOPK protein and transcriptional levels of FOXM1 (show FOXM1 Antibodies) were reduced by TOPK inhibitor treatment.

  7. Results indicate that src (show SRC Antibodies)-family kinase (Src (show SRC Antibodies)) is a upstream kinase of T-LAK cell-originated protein kinase (TOPK).

  8. Upregulation of proteasome subunit beta type 8 PSMB8 (show PSMB8 Antibodies) and PDZ binding kinase PBK was confirmed by real-time reverse transcription-PCR analysis.

  9. MiR (show MLXIP Antibodies)-770-5p and PBK levels were inversely correlated in xenograft model mice.

  10. TOPK knockdown did not alter radiation response in normal tissues, but significantly enhanced radiosensitivity in cancer cells.These findings have clinical relevance, as elevated TOPK protein expression was associated with poorer clinical outcomes in prostate cancer patients treated with radical radiotherapy. TOPK disruption may cause tumour-specific radiosensitisation in multiple different tumour types.

Mouse (Murine) PDZ Binding Kinase (PBK) interaction partners

  1. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK/PTEN/Akt (show AKT1 Antibodies) signaling pathway

  2. T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 (show DUSP1 Antibodies) protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein (show RNF19A Antibodies) signaling pathway.

  3. The TOPK protein is expressed mainly in the cytosol of spermatocytes and spermatids, but not in spermatids and spermatogonia in situ.

  4. Melanoma cell lines expressing with high levels of TOPK are more resistant to As(3+)-induced apoptosis. Therefore, inhibition of TOPK activity combined with As(3+) treatment may be helpful in the treatment of melanomas.

PDZ Binding Kinase (PBK) Antigen Profile

Protein Summary

This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Gene names and symbols associated with PBK

  • PDZ binding kinase (PBK) antibody
  • PDZ binding kinase (pbk) antibody
  • PDZ binding kinase (Pbk) antibody
  • PDZ binding kinase L homeolog (pbk.L) antibody
  • 2810434B10Rik antibody
  • AW538537 antibody
  • CT84 antibody
  • D14Ertd732e antibody
  • Nori-3 antibody
  • PBK antibody
  • SPK antibody
  • TOPK antibody
  • zgc:92050 antibody

Protein level used designations for PBK

PDZ binding kinase , T-LAK cell-originated protein kinase , MAPKK-like protein kinase , cancer/testis antigen 84 , lymphokine-activated killer T-cell-originated protein kinase , serine/threonine protein kinase , spermatogenesis-related protein kinase , PDZ-binding kinase , PBK, PDZ-binding kinase , lymphokine-activated killer T-cell-originated protein kinase homolog

GENE ID SPECIES
422003 Gallus gallus
464496 Pan troglodytes
496810 Xenopus (Silurana) tropicalis
713242 Macaca mulatta
100341076 Oryctolagus cuniculus
100587879 Nomascus leucogenys
55872 Homo sapiens
52033 Mus musculus
360218 Danio rerio
496340 Xenopus laevis
477371 Canis lupus familiaris
100141310 Sus scrofa
534781 Bos taurus
290326 Rattus norvegicus
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