PBK Products
(PDZ Binding Kinase (PBK))
Categories
This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. [provided by RefSeq, Jul 2008].
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Featured PBK Categories
PBK Antibodies
High quality antibodies with extensive validation data.
PBK ELISA Kits
Reliable ELISA kits for a wide range of species.
PBK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PBK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN969345
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (7)
Cat. No.
ABIN527757
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (2)
- (4)
Cat. No.
ABIN1881635
Quantity
400 μL
Datasheet
Datasheet
Recommended PBK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380317
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951206
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1141112
Quantity
96 tests
Datasheet
Datasheet
Recommended PBK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569604
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5569603
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124331
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PBK products
: "Critical roles of T-LAK cell-originated protein kinase in cytokinesis." in: Cancer science, Vol. 101, Issue 2, pp. 403-11, (2010) (PubMed).: "Tissue profiling of the mammalian central nervous system using human antibody-based proteomics." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1612-22, (2009) (PubMed).
: "T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation." in: Cancer research, Vol. 67, Issue 11, pp. 5186-94, (2007) (PubMed).
: "Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 23, pp. 6884-93, (2006) (PubMed).
: "Expression and phosphorylation of TOPK during spermatogenesis." in: Development, growth & differentiation, Vol. 47, Issue 9, pp. 637-44, (2005) (PubMed).
: "Protein expression of PDZ-binding kinase is up-regulated in hematologic malignancies and strongly down-regulated during terminal differentiation of HL-60 leukemic cells." in: Blood cells, molecules & diseases, Vol. 32, Issue 1, pp. 240-5, (2004) (PubMed).
: "PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells." in: Blood cells, molecules & diseases, Vol. 27, Issue 5, pp. 825-9, (2002) (PubMed).
: "PDZ-binding kinase participates in spermatogenesis." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 6, pp. 631-6, (2001) (PubMed).
: "Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells." in: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21525-31, (2000) (PubMed).
: "Characterization of PDZ-binding kinase, a mitotic kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 10, pp. 5167-72, (2000) (PubMed).
Synonyms and alternative names related to PBK
PDZ binding kinase (PBK), PDZ binding kinase (pbk), PDZ binding kinase (Pbk), PDZ binding kinase L homeolog (pbk.L), 2810434B10Rik, AW538537, CT84, D14Ertd732e, Nori-3, PBK, SPK, topk, TOPK, zgc:92050Protein level used designations for PBK
- PDZ binding kinase
- T-LAK cell-originated protein kinase
- MAPKK-like protein kinase
- cancer/testis antigen 84
- lymphokine-activated killer T-cell-originated protein kinase
- serine/threonine protein kinase
- spermatogenesis-related protein kinase
- PDZ-binding kinase
- PBK, PDZ-binding kinase
- lymphokine-activated killer T-cell-originated protein kinase homolog
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