anti-PDZ and LIM Domain 2 (Mystique) (PDLIM2) Antibodies

PDLIM2 encodes a member of the ALP subfamily of PDZ-LIM domain proteins. Additionally we are shipping PDLIM2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDLIM2 213019 Q8R1G6
PDLIM2 290354 Q6AYD6
PDLIM2 64236 Q96JY6
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Top anti-PDLIM2 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Dog Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Details
Dog Mouse Un-conjugated FACS, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454447) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 0.1 mL 2 to 3 Days
$462.00
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-PDLIM2 mouse monoclonal antibody. (ABIN2454449) 0.1 mL 2 to 3 Days
$462.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454448) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 0.1 mL 2 to 3 Days
$462.00
Details

Top referenced anti-PDLIM2 Antibodies

  1. Human Polyclonal PDLIM2 Primary Antibody for WB - ABIN528596 : Zhao, Yasunaga, Satou, Nakao, Takahashi, Fujii, Matsuoka: Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. in Blood 2009 (PubMed)

More Antibodies against PDLIM2 Interaction Partners

Mouse (Murine) PDZ and LIM Domain 2 (Mystique) (PDLIM2) interaction partners

  1. Reducing NF-kappaB activation attenuates PDLIM2 deficiency-exacerbated inflammation and dyslipidemia in Palmitate -treated primary hepatocytes.

  2. Klotho can modulate inflammation via PDLIM2/NF-kappaB p65 pathway in cyclosporine A-induced nephropathy.

  3. Deficiency in PDLIM2 resulted in the accumulation of STAT3 in the nucleus, enhanced the extent of TH17 cell differentiation, and exacerbated granuloma formation.

  4. Pdlim2 is a novel actin-regulating protein of podocyte foot processes that may have a role in the pathogenesis of glomerular diseases.

  5. PDLIM2 expression was sufficient to suppress in vitro anchorage-independent growth and in vivo tumor formation of colon cancer. PDLIM2 repression involves promoter methylation.

  6. Knockdown of Mystique 2 with small interfering RNA abrogated both adhesion and migration in MCF10A and MCF-7 cells

  7. SLIM is a novel ubiquitin E3 ligase whose targets include STAT proteins.

  8. PDLIM2 deficiency resulted in larger amounts of nuclear p65, defective p65 ubiquitination and augmented production of proinflammatory cytokines in response to innate stimuli

  9. Stat-interacting LIM protein as the critical Stat ubiquitin E3 ligase involved in osteopontin regulation of Stat1.

  10. Suppression of PDLIM2 expression resulted in decreased cell adhesion, increased NF-kappaB transcription reporter activity, and increased LPS-induced TNF-alpha production.

Human PDZ and LIM Domain 2 (Mystique) (PDLIM2) interaction partners

  1. The results showed that (i) the use of SPR chip led to comparable data compared to on-column streptavidin beads, (ii) gravity flow and microflow in wash and elution steps provided better results than centrifugation, and (iii) type and concentration of detergent did not significantly affect the interactome data of cancer-associated PDLIM2.

  2. Data indicate that OR3A4 upregulation contributes to metastasis and tumorigenesis in gastric cancer by regulating the activation of PDLIM2, MACC1, NTN4, and GNB2L1.

  3. We conclude that inactivation of PDLIM2 is a recurrent finding in cHL and ALCL, promotes activation of inflammatory signaling pathways and thereby contributes to their pathogenesis

  4. Data show that shRNA mediated knockdown of PDZ and LIM domain protein 2 (PDLIM2) in both primary meningioma and schwannoma leads to significant reductions in cellular proliferation.

  5. PDLIM2 is epigenetically repressed in ovarian cancer development and inhibition of PDLIM2 promoted ovarian cancer growth both in vivo and in vitro via NOS2-derived nitric oxide signaling, leading to recruitment of M2 type macrophages.

  6. The suppression of PDLIM2 expression significantly reduced cell proliferation, cell growth and neoplasm invasiveness in prostate cancer cells.

  7. epigenetic repression of PDLIM2 can be reversed by 5-aza-2-deoxycytidine and vitamin D to suppress KSHV-associated cancer cell growth

  8. PDLIM2 expression is essential for feedback regulation of the beta1-integrin-RhoA signalling axis and integration of cellular microenvironment signals with gene expression to control the polarity of breast epithelial acini structures.

  9. PDLIM2 integrates cytoskeleton signaling with gene expression in epithelial differentiation by controlling the stability of key transcription factors and COP9 signalosome activity.

  10. PDLIM2 was a direct target gene of 1,25(OH)2D3

  11. Pdlim2 is a novel actin-regulating protein of podocyte foot processes that may have a role in the pathogenesis of glomerular diseases.

  12. PDLIM2 binds to Tax directly, which was mediated by a putative alpa-helix motif of PDLIM2 at amino acids 236-254.

  13. PDLIM2, an essential terminator of NF-kappaB activation, is repressed in both estrogen receptor-positive and estrogen receptor-negative breast cancer cells, suggesting one important mechanism for the constitutive activation of NF-kappaB.

  14. Data show that the PDLIM2 repression was independent of the viral regulatory protein Tax because neither short-term induction nor long-term stable expression of Tax could downregulate PDLIM2 expression.

  15. Knockdown of Mystique 2 with small interfering RNA abrogated both adhesion and migration in MCF10A and MCF-7 cells

  16. PDLIM2 deficiency resulted in larger amounts of nuclear p65, defective p65 ubiquitination and augmented production of proinflammatory cytokines in response to innate stimuli

  17. Suppression of PDLIM2 expression resulted in decreased cell adhesion, increased NF-kappaB transcription reporter activity, and increased LPS-induced TNF-alpha production.

PDLIM2 Antigen Profile

Protein Summary

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PDLIM2

  • PDZ and LIM domain 2 (Pdlim2) antibody
  • PDZ and LIM domain 2 (PDLIM2) antibody
  • 4732462F18Rik antibody
  • MYSTIQUE antibody
  • SLIM antibody

Protein level used designations for PDLIM2

PDZ and LIM domain protein 2 , PDZ-LIM protein mystique , STAT-interacting LIM protein , mystique , alpha-actinins and filamin-interacting protein

GENE ID SPECIES
213019 Mus musculus
290354 Rattus norvegicus
64236 Homo sapiens
512907 Bos taurus
486123 Canis lupus familiaris
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