PDLIM2 antibody (N-Term)

Catalog No. ABIN5514410

The Rabbit Polyclonal anti-PDLIM2 antibody (ABIN5514410) specifically detects PDLIM2 in WB. The antibody is reactive with Human samples.

Quick Overview for PDLIM2 antibody (N-Term) (ABIN5514410)

Target: PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDLIM2 Antibody

Binding Specificity: N-Term

Purpose: PDLIM2 Antibody - N-terminal region

Sequence: LHAEAQSKIR QSPSPLRLQL DRSQATSPGQ TNGDSSLEVL ATRFQGSVRT

Characteristics: This is a rabbit polyclonal antibody against PDLI2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDLI2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75739-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDLIM2

Target: PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))

Alternative Name: PDLIM2

Background:

Background Information: This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: PDZ and LIM domain 2

Alternative Symbols: SLIM, MYSTIQUE

Protein Name: PDZ and LIM domain protein 2

Molecular Weight: 38kDa

Gene ID: 64236

UniProt: Q96JY6