anti-PHD Finger Protein 2 (PHF2) Antibodies

PHF2 encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. Additionally we are shipping PHF2 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHF2 5253 O75151
PHF2 18676 Q9WTU0
PHF2 306814  
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Top anti-PHF2 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHF2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Western blot analysis of PHF2 monoclonal antibody  at 1 : 2000 dilution interacts with recombinant PHF2 protein with a GST tag. Predicted band size : 80 KDa. Observed band size : 80 KDa. 100 μg 11 to 12 Days
$356.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.63 KDa) . 200 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg 11 to 14 Days
$419.83
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunofluorescent staining of human cell line U-2 OS with PHF2 polyclonal antibody  shows positivity in nucleus and nucleoli. Antibody staining is shown in green. Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with PHF2 polyclonal antibody  shows strong nuclear positivity in exocrine glandular cells and islet cells. 100 μL 11 to 12 Days
$577.33
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$595.83
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 16 Days
$581.43
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details

More Antibodies against PHF2 Interaction Partners

Human PHD Finger Protein 2 (PHF2) interaction partners

  1. PHF2 is a negative epigenetic regulator of MK and erythroid differentiation.

  2. Our results demonstrate that the IKAROS promotes PHF2 expression, and suggest that PHF2 (low) expression works with the IKAROS gene deletion to drive oncogenesis of ALL

  3. Frameshift mutations of PHF2 may play a role in tumorigenesis through its TSG inactivation in CRC and GC.

  4. PHF2 acts as a tumor suppressor in association with p53 in cancer development and ensures p53-mediated cell death in response to chemotherapy.

  5. PHF2 is likely to repress rDNA transcription by competing with PHF8 for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1.

  6. JARID1B and PHF2 are overexpressed in esophageal squamous cell carcinoma (ESCC) and they may play crucial roles in the course of ESCC initiation and/or progression

  7. the crystal structures of PHF2 Jumonji domain in the absence and presence of additional exogenous metal ions were determined.

  8. Differential association of alterations in FANCC and PTCH1 with that of PHF2, XPA and two breast cancer susceptibility genes (BRCA1/BRCA2) in the two age groups suggests differences in their molecular pathogenesis.

Mouse (Murine) PHD Finger Protein 2 (PHF2) interaction partners

  1. The paper's findings establish a downstream epigenetic checkpoint, whereby Phf2, through facilitating H3K9me2 demethylation at specific gene promoters, protects liver from the pathogenesis progression of Non-alcoholic Fatty Liver Disease.

  2. these results demonstrate that PHF2 histone demethylase controls adipogenic gene expression during differentiation.

  3. PHF2 enhances osteoblast differentiation by demethylating Runx2, while suppressor of variegation 3-9 homolog 1 (SUV39H1) inhibits bone formation by methylating it.

  4. Arid5b recruits Phf2 to the promoter region of Sox9 target genes and stimulates H3K9me2 demethylation of these genes.

  5. Data from PHF2 knockout mice suggest that PHF2 plays roles in both adipogenesis and neonatal growth/weight gain; PHF2 interacts with promoter region of CEBPA (CCAAT-enhancer binding protein alpha) gene and demethylates histones in chromatin.

  6. histone H3K4 trimethylation by a homeodomain of PHF2 modulates histone demethylation

PHF2 Antigen Profile

Protein Summary

This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.

Gene names and symbols associated with PHF2

  • PHD finger protein 2 (PHF2) antibody
  • PHD finger protein 2 (Phf2) antibody
  • PHD finger protein 2 (phf2) antibody
  • CENP-35 antibody
  • GRC5 antibody
  • im:4200679 antibody
  • JHDM1E antibody
  • phf8 antibody
  • wu:fa14c10 antibody

Protein level used designations for PHF2

centromere protein 35 , jumonji C domain-containing histone demethylase 1E , lysine-specific demethylase PHF2 , PHD finger protein 8 , lysine-specific demethylase phf2 , PHD finger protein 2

GENE ID SPECIES
5253 Homo sapiens
18676 Mus musculus
503778 Danio rerio
415981 Gallus gallus
306814 Rattus norvegicus
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