PHF2 antibody

Catalog No. ABIN7465155

Product Details anti-PHF2 Antibody

Target: PHF2 (PHD Finger Protein 2 (PHF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PHF2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PHF2

Target: PHF2 (PHD Finger Protein 2 (PHF2))

Alternative Name: PHD finger protein 2 (PHF2 Products)

Synonyms: CENP-35 antibody, GRC5 antibody, JHDM1E antibody, im:4200679 antibody, phf8 antibody, wu:fa14c10 antibody, PHD finger protein 2 antibody, PHF2 antibody, Phf2 antibody, phf2 antibody

Background: PHD finger protein 2 , CENP-35 , GRC5 , JHDM1E , KDM7C,Probable regulator of histone methyltransferase complexes. Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. Was reported to have histone demethylase activity by itself and specifically demethylate monomethylated 'Lys-9' of histone H3 (H3K9me1), an epigenetic repressive mark. However, this activity is unclear in vivo and requires additional evidence.

Molecular Weight: 121 kDa

Gene ID: 5253

UniProt: O75151