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Microtubule-binding protein essential for faithful chromosome segregation. Additionally we are shipping PINX1 Antibodies (73) and PINX1 Kits (3) and many more products for this protein.
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The cost-effective expression of PinX1 could constitute a novel molecular predictor/marker for NSCLC management.
PINX1 Polymorphisms are associated with Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection.
The stability of PinX1 is maintained in nucleolus in the presence of TERT (show TERT Proteins).
PinX1 negatively regulated ccRCC metastasis and the expression of MMP-2 (show MMP2 Proteins) and NF-kappaB (show NFKB1 Proteins)-p65 (show GORASP1 Proteins)
High PinX1 expression significantly correlated with a worse 5-year overall and disease-specific survival in gliomas.
Data show a novel molecular mechanism for PINX1 as an attenuator of estrogen receptor (show ESR1 Proteins) activity in breast cancer cell lines, furthering its role as a tumor suppressor gene in breast cancer.
PinX1 protein expression is decreased in colorectal cancer patients and predicts a poor prognosis.
PinX1 inhibits cell proliferation, migration and invasion in glioma cells.
PinX1 expression was an independent negative prognostic factor for breast cancer patients.
Two novel markers, rs7840785 (PINX1) and rs7844465 (ZHX2 (show ZHX2 Proteins)), are significantly associated with carotid intima-media thickness.
PinX1 heterozygosity and PinX1 knockdown in mouse embryonic fibroblasts activated telomerase and led to concomitant telomerase-dependent chromosomal instability.
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).
PIN2-interacting protein 1
, 67-11-3 protein
, PIN2 interacting protein 1
, PIN2/TERF1-interacting telomerase inhibitor 1
, TRF1-interacting protein 1
, hepatocellular carcinoma-related putative tumor suppressor
, liver-related putative tumor suppressor
, pin2-interacting protein X1
, protein 67-11-3
, PIN2-interacting protein X1
, PIN2/TRF1-interacting protein
, Pin2-interacting protein X1