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The protein encoded by PPIC is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. Additionally we are shipping Peptidylprolyl Isomerase C (Cyclophilin C) Proteins (12) and Peptidylprolyl Isomerase C (Cyclophilin C) Kits (7) and many more products for this protein.
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Independent validation with glioma patients tissue (n = 70) and normal brain tissue (n = 19) found PPIC, EMP3 and CHI3L1 were up-regulated in glioma tissue. Survival value validation showed that the three genes correlated with patient survival by Kaplan-Meir analysis, including grades, age and therapy.
Cyclophilin C participates in cytomegalovirus US2 protein-mediated degradation of major histocompatibility complex class I molecules.
These findings establish cyclophilin C as an ER cyclophilin, demonstrate the novel involvement of cyclophilins B and C in ER redox homeostasis
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase PPIase family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A.
peptidylprolyl isomerase C (cyclophilin C)
, peptidyl-prolyl cis-trans isomerase C
, cyclophilin C
, PPIase C
, rotamase C