anti-Phosducin-Like (PDCL) Antibodies

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. Additionally we are shipping Phosducin-Like Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDCL 5082 Q13371
PDCL 64013 Q63737
PDCL 67466 Q9DBX2
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Top anti-Phosducin-Like Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image PHLP antibody detects PHLP protein at cytoplasm on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. PHLP antibody , dilution: 1:500. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PHLP, antibody at 1:200 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PDCL Antibody [NBP1-32523] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution. Western Blot: PDCL Antibody [NBP1-32523] - Sample(30 ug whole cell lysate)A:H129910% SDS PAGE, antibody diluted at 1:3000. 100 μL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated WB Immunohistochemical analysis of paraffin-embedded H.kidney section using PDCL Antibody (N-term)(ABIN2838520). ABIN2838520 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti PHLP Polyclonal Antibody,Unconjugated (ABIN715121) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: rat brain lysates Lane 2: rat kidney lysates probed with Anti PHLP Polyclonal Antibody, Unconjugated (ABIN715121) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 85kD. Observed band size: 85kD. 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PDCL Antibody [NBP1-85079] - Staining of human cell line U-251 MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: PDCL Antibody [NBP1-85079] - Staining of human skeletal muscle shows distinct cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: PDCL Antibody [NBP1-85078] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm & centrosome. Immunohistochemistry-Paraffin: PDCL Antibody [NBP1-85078] - Staining of human kidney shows strong cytoplasmic positivity in tubular cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of HeLa cells, using PDCL antibody (ABIN5972175). 100 μL Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 11 to 14 Days
$507.83
Details

Top referenced anti-Phosducin-Like Antibodies

  1. Human Polyclonal PDCL Primary Antibody for WB - ABIN1944777 : Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ... in Genome research 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PDCL Primary Antibody for ICC, IF - ABIN4344392 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against Phosducin-Like Interaction Partners

Human Phosducin-Like (PDCL) interaction partners

  1. PhLP1 binding stabilizes the Gbeta fold, disrupting interactions with CCT and releasing a PhLP1-Gbeta dimer for assembly with Ggamma.

  2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  3. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 and alternative splicing of the regulator

  4. the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha

  5. PhLP phosphorylation permits the release of a PhLP x Gbeta intermediate from cytosolic chaperonin complex, allowing Ggamma to associate with Gbeta in this intermediate complex.

  6. cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way

  7. PhLP-M1-G149, a Gbetagamma-interacting construct derived from phosducin-like protein 1 (PhLP) is a differential inhibitor of Gbetagamma

Mouse (Murine) Phosducin-Like (PDCL) interaction partners

  1. Pdcl has been implicated as a positive regulator of Hedgehog signaling that may control the trafficking of signaling receptors to primary cilia.

  2. findings reveal a common mechanism of Gbetagamma and RGS9-Gbeta5 assembly in rods and cones, highlighting the importance of PhLP1 and CCT-mediated Gbeta complex formation in G protein signaling.

  3. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  4. this study demonstrated in vivo that PhLP1 is required for the folding and assembly of both Gbetagamma and Gbeta5-RGS9.

  5. These data are consistent with the hypothesis that PhLP is a widely expressed modulator of Gbetagamma function.

  6. These results suggest a mechanism for Gbetagamma assembly in which PhLP stabilizes the nascent Gbeta polypeptide until Ggamma can associate, resulting in membrane binding of Gbetagamma and release of PhLP to catalyze another round of assembly.

  7. N-glycosylated phosducin-like protein long (PhLP(L)) is expressed in all structures of the central nervous system and regulates opioid receptor function in the brain.

  8. identification of novel germ-like specific form in phosducin-like protein family

  9. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 and alternative splicing of the regulator

Cow (Bovine) Phosducin-Like (PDCL) interaction partners

  1. antagonistic actions of PhLP3 and prefoldin serve to modulate CCT activity and play a key role in establishing a functional cytoskeleton in vivo

Phosducin-Like (PDCL) Antigen Profile

Protein Summary

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.

Gene names and symbols associated with anti-Phosducin-Like (PDCL) Antibodies

  • phosducin like (PDCL) antibody
  • phosducin-like (Pdcl) antibody
  • phosducin like (pdcl) antibody
  • phosducin-like (pdcl) antibody
  • 1200011E13Rik antibody
  • AW108059 antibody
  • fc06a08 antibody
  • im:6793474 antibody
  • Phlp antibody
  • PhLP1 antibody
  • wu:fc06a08 antibody
  • zgc:73264 antibody

Protein level used designations for anti-Phosducin-Like (PDCL) Antibodies

phosducin-like protein , PHLP , phosducin-like

GENE ID SPECIES
5082 Homo sapiens
64013 Rattus norvegicus
67466 Mus musculus
548824 Xenopus (Silurana) tropicalis
286773 Bos taurus
323645 Danio rerio
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