anti-Poly(rC) Binding Protein 2 (PCBP2) Antibodies

The protein encoded by PCBP2 appears to be multifunctional. Additionally we are shipping PCBP2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PCBP2 5094 Q15366
PCBP2 18521 Q61990
PCBP2 363005  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top anti-PCBP2 Antibodies at

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PCBP2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PCBP2 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated WB PCBP2 monoclonal antibody (M02), clone 1B6. Western Blot analysis of PCBP2 expression in K-562. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of hnRNP E2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo 200 μL Log in to see 13 to 14 Days
Cow Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry: PCBP2 Antibody [NBP1-83241] - Immunofluorescence: [NBP1-83241] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: PCBP2 Antibody [NBP1-83241] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2, antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 1 to 2 Days
Human Mouse Un-conjugated IF, IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PCBP2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days

PCBP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
, , , , ,
Mouse (Murine)

Rat (Rattus)

Top referenced anti-PCBP2 Antibodies

  1. Human Monoclonal PCBP2 Primary Antibody for IF, IHC (p) - ABIN562121 : Fujimura, Kano, Murata: Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies. in RNA (New York, N.Y.) 2008 (PubMed)
    Show all 9 Pubmed References

  2. Cow (Bovine) Polyclonal PCBP2 Primary Antibody for IHC, WB - ABIN2778923 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal PCBP2 Primary Antibody for ICC, IF - ABIN4344023 : Flynn, Martin, Spitale, Do, Sagan, Zarnegar, Qu, Khavari, Quake, Sarnow, Chang: Dissecting noncoding and pathogen RNA-protein interactomes. in RNA (New York, N.Y.) 2014 (PubMed)

  4. Human Monoclonal PCBP2 Primary Antibody for WB - ABIN394008 : Kim, Chang, Yun, Yang, Hong, Kim, Um, Lee, Lee, Hwang: Chloride intracellular channel 1 identified using proteomic analysis plays an important role in the radiosensitivity of HEp-2 cells via reactive oxygen species production. in Proteomics 2010 (PubMed)

More Antibodies against PCBP2 Interaction Partners

Human Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. Double immunofluorescence for hnRNP E2 and TDP-43 (show TARDBP Antibodies) showed most TDP-43 (show TARDBP Antibodies) immunopositive dystrophic neuritis within frontal and temporal cortex, and the neuronal cytoplasmic inclusions seen in dentate gyrus granule cells, to contain hnRNP E2. Present findings indicate an association between TDP-43 (show TARDBP Antibodies) and hnRNP E2 which might underlie the pathogenetic mechanism of Semantic Dementia Frontotemporal Lobar Degeneration.

  2. Data suggest that the interaction between PCBP2 and the 3'UTR (show UTS2R Antibodies) of the ARHGDIA (show ARHGDIA Antibodies) mRNA may induce a local change in RNA structure that favors subsequent binding of miR (show MLXIP Antibodies)-151-5p and miR-16 (show GDE1 Antibodies), thus leading to the suppression of ARHGDIA (show ARHGDIA Antibodies) expression.

  3. To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 competes with CPR (show POR Antibodies) for binding HO1 (show HMOX1 Antibodies); PCBP2 K homology 3 domain is important for HO1 (show HMOX1 Antibodies)/PCBP2 interaction; heme prompts HO1 (show HMOX1 Antibodies)/CPR (show POR Antibodies) multimer and decreases HO1 (show HMOX1 Antibodies)/PCBP2 multimer. [PCBP2 = poly(rC) binding protein 2; CPR (show POR Antibodies) = cytochrome P450 reductase (show POR Antibodies); HO1 (show HMOX1 Antibodies) = heme oxidase 1]

  4. BC200 RNA interacts with hnRNP E1 (show PCBP1 Antibodies) and E2 mainly through its unique 3' C-rich domain.

  5. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  6. These results suggest that FPN1 (show SLC40A1 Antibodies) exports iron received from the iron chaperone PCBP2. Therefore, it was found that PCBP2 modulates cellular iron export, which is an important physiological process.

  7. PCBP2 was overexpressed in esophageal squamous cell carcinoma tissues and cell lines. PCBP2 expression promoted proliferation of ESCC cells. We also found that reduced PCBP2 expression might induce ESCC cell apoptosis with increased cleaved caspase3 expression. Overall, our findings indicated that PCBP2 might be involved in the ESCC progression and be considered as a new treatment target in ESCC.

  8. High expression of PCBP2 may contribute to sorafenib resistance in hepatocellular carcinoma cells.

  9. our data indicate that miR (show MLXIP Antibodies)-214 may function as tumor suppressor in glioma by targeting PCBP2

  10. beta2-adrenergic receptor (show ADRB2 Antibodies) signaling promotes pancreatic ductal adenocarcinoma progression by facilitating PCBP2-dependent c-myc (show MYC Antibodies) expression.

Mouse (Murine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  2. data suggest that PCBP2 regulates p73 (show ARHGAP24 Antibodies) expression via mRNA stability and p73 (show ARHGAP24 Antibodies)-dependent biological function in ROS (show ROS1 Antibodies) production and cellular senescence.

  3. PCBP2 overexpression rescues the Meis1 (show MEIS1 Antibodies) effects of Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway and hypertrophy of cardiomyocytes.

  4. These data reveal that Pcbp1 (show PCBP1 Antibodies) and Pcbp2 are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.

  5. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

  6. Our analysis of PCBP1 (show PCBP1 Antibodies) and PCBP2 expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.

  7. This study demonstrates for the first time that alpha-CP2 functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.

  8. This study provides evidence that PCBP2 and hnRNP A1 (show HNRNPA1 Antibodies) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  9. PCBP2-AIP4 (show ITCH Antibodies) axis defines a new signaling cascade for MAVS (show MAVS Antibodies) degradation and 'fine tuning' of antiviral innate immunity.

Pig (Porcine) Poly(rC) Binding Protein 2 (PCBP2) interaction partners

  1. These results indicated that Nsp1beta of porcine reproductive and respiratory syndrome virus is able to bind and interact with cellular PCBP2 strongly in both the infected cells and plasmid transfected cells.

  2. Overall, the results presented here point toward an important role for PCBP1 (show PCBP1 Antibodies) and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.

PCBP2 Antigen Profile

Protein Summary

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PCBP2

  • poly(rC) binding protein 2 (PCBP2) antibody
  • poly(rC) binding protein 2 (Pcbp2) antibody
  • poly(rC) binding protein 2 (pcbp2) antibody
  • poly(rC) binding protein 2 L homeolog (pcbp2.L) antibody
  • alphaCP-2 antibody
  • AW412548 antibody
  • fb36h02 antibody
  • hnRNP-E2 antibody
  • HNRNPE2 antibody
  • HNRPE2 antibody
  • Hnrpx antibody
  • PCBP2 antibody
  • PCBP3 antibody
  • wu:fb36h02 antibody
  • zgc:55964 antibody

Protein level used designations for PCBP2

alpha-CP2 , heterogeneous nuclear ribonucleoprotein E2 , heterogenous nuclear ribonucleoprotein E2 , hnRNP E2 , poly(rC)-binding protein 2 , CBP , CTBP , heterogeneous nuclear ribonucleoprotein X , hnRNP X , putative heterogeneous nuclear ribonucleoprotein X , poly(rC) binding protein 2 , poly(rC) binding protein 3 , PolyrC-binding protein 2 , poly(rc)-binding protein 2 , heterogeneous nuclear ribonucleoprotein

5094 Homo sapiens
18521 Mus musculus
321844 Danio rerio
363005 Rattus norvegicus
399399 Xenopus laevis
420965 Gallus gallus
477596 Canis lupus familiaris
540653 Bos taurus
733863 Xenopus (Silurana) tropicalis
100194880 Salmo salar
100528911 Ictalurus punctatus
397665 Sus scrofa
100731593 Cavia porcellus
Selected quality suppliers for anti-PCBP2 (PCBP2) Antibodies
Did you look for something else?