PCBP2 antibody (AA 171-293)

Catalog No. ABIN7163773

Product Details anti-PCBP2 Antibody

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Binding Specificity: AA 171-293

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Poly(rC)-binding protein 2 protein (171-293AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PCBP2

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Alternative Name: PCBP2 (PCBP2 Products)

Synonyms: HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody

Background:

Background: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).

Aliases: Alpha CP2 antibody, Alpha-CP2 antibody, alphaCP-2 antibody, Cbp antibody, CTBP antibody, Heterogeneous nuclear ribonucleoprotein E2 antibody, Heterogenous nuclear ribonucleoprotein E2 antibody, hnRNP E2 antibody, hnRNP-E2 antibody, HNRNPE2 antibody, Hnrnpx antibody, HNRPE2 antibody, Hnrpx antibody, MGC110998 antibody, PCBP2 antibody, PCBP2_HUMAN antibody, poly(rC) binding protein 2 antibody, Poly(rC)-binding protein 2 antibody, Putative heterogeneous nuclear ribonucleoprotein X antibody, rCbinding protein 2 antibody

UniProt: Q15366