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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) Antibodies

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Additionally we are shipping Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Proteins (4) and Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNA5 3741 P22460
KCNA5 16493 Q61762
KCNA5 25470 P19024
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Top anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-KCNA5 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Kv1.5 expression in MCF7 (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated WB KCNA5 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the KCNA5 antibody detected the KCNA5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-KCNA5 / Kv1.5 antibody IHC staining of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1102664 concentration 10 ug/ml. 100 μL Log in to see 7 to 9 Days
$639.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$181.73
Details

KCNA5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Antibodies

  1. Mammalian Monoclonal KCNA5 Primary Antibody for ISt, IHC - ABIN1304754 : Pott, Ren, Tran, Yang, Henderson, Jordan, Roos, Garfinkel, Philipson, Goldhaber: Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice. in American journal of physiology. Cell physiology 2007 (PubMed)
    Show all 14 Pubmed References

  2. Human Polyclonal KCNA5 Primary Antibody for WB - ABIN610625 : OSullivan, Kennedy, Casey, Day, Corrigan, Wodak: Anabolic-androgenic steroids: medical assessment of present, past and potential users. in The Medical journal of Australia 2000 (PubMed)
    Show all 4 Pubmed References

  3. Cow (Bovine) Polyclonal KCNA5 Primary Antibody for IP, WB - ABIN449232 : Zhou, Ma, Huang: Specific antibodies to the external vestibule of voltage-gated potassium channels block current. in The Journal of general physiology 1998 (PubMed)

  4. Dog (Canine) Polyclonal KCNA5 Primary Antibody for IF (p), IHC (p) - ABIN735158 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

More Antibodies against Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 Interaction Partners

Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. our finding indicated that KCNA5 protein may interact with Cav-1 (show CAV1 Antibodies), thereby contributing to the proliferation and early transformation of mammary cells.

  2. Studies demonstrate that DNA hypermethylation contributes to epigenetic repression of the KCNA5 locus and that the resulting suppression of the Kv1.5 ion channel supports cancer cell proliferation.

  3. Kv1.5 expression is increased in osteosarcoma cells and tissues and shRNA mediated silencing of Kv1.5 results in cell proliferation inhibition, cell cycle arrest, and induces cell apoptosis.

  4. demonstrate that PK treatment cleaved mature membrane-bound (75kDa (show INPP5B Antibodies)) Kv1.5 channels at a single locus in the S1-S2 linker, producing 42-kDa N-terminal fragments and 33-kDa C-terminal fragments

  5. These results indicate that CHIP decreases the Kv1.5 protein level and functional channel by facilitating its degradation in concert with chaperone Hsc70 (show HSPA8 Antibodies)

  6. The expression of Kv1.5 channel protein changes with atrial fibrillation but not with age, rheumatic heart diseases, and sex in atrial fibrillation.

  7. One KCNA5 variant, H463R, was a novel mutation; the histidine at codon 463 is located in the S5-pore loop, in the vicinity of the pore of KV1.5 subunit. The other variant, T527M, showed a gain-of-function effect with an enhanced steady-state activation.

  8. The KCNA5 promoter is marked in cancer cells with PcG-dependent chromatin repressive modifications that increase in hypoxia.

  9. Mutations in KCNA5 gene is not associated with pulmonary arterial hypertension.

  10. Protein kinase C (show PKC Antibodies) inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. KV1.5 channels predominantly associate with KVbeta1 (show KCNAB1 Antibodies) and KVbeta2 (show KCNAB2 Antibodies) proteins and that KVbeta2 (show KCNAB2 Antibodies) performs a chaperone function for KV1.5 channels in arterial myocytes, thereby facilitating Kv1alpha trafficking and membrane localization.

  2. Silencing of Kv1.5 improved endothelium-dependent vasodilatation in thoracic aorta from type 2 diabetes mice.

  3. Intracellular urate taken up by UATs enhanced Kv1.5 protein expression and function in HL-1 (show ASGR1 Antibodies) atrial myocytes.

  4. JAK3 (show JAK3 Antibodies) contributes to the regulation of membrane Kv1.5 protein abundance and activity, an effect sensitive to ouabain and thus possibly involving Na(+)/K(+) ATPase (show ATP1A1 Antibodies) activity.

  5. KV1.5, a DPO-1-sensitive KDR (show KDR Antibodies) channel, plays a major role in determining microvascular tone and the response to vasoconstrictors and vasodilators.

  6. Kv1.5 channels in vascular smooth muscle play a critical role in coupling myocardial blood flow to cardiac metabolism.

  7. the Kv1.5 subunit has a role in electrical remodeling of preoptic GABAergic neurons

  8. MYO5A (show MYO5A Antibodies) and MYO5B control functionally distinct steps in the surface trafficking of Kv1.5.

  9. e-LXA4 promoted a modest upregulation of Kv1.5 mRNA that was suppressed by LPS (show TLR4 Antibodies) or IL-4 (show IL4 Antibodies)/IL-13 (show IL13 Antibodies).

  10. The combined down-regulation of Kv4.2 (show KCND2 Antibodies), Kv1.5 and KChIP2 (show KCNIP2 Antibodies) prior to the onset of HF may play an important role in the premature sudden death in this DCM model.

Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) Antigen Profile

Protein Summary

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).

Gene names and symbols associated with KCNA5

  • potassium voltage-gated channel subfamily A member 5 (KCNA5) antibody
  • potassium channel, voltage gated shaker related subfamily A, member 5 (kcna5) antibody
  • potassium voltage-gated channel, shaker-related subfamily, member 5 (Kcna5) antibody
  • potassium voltage-gated channel subfamily A member 5 (Kcna5) antibody
  • ATFB7 antibody
  • HCK1 antibody
  • HK2 antibody
  • HPCN1 antibody
  • kcna5 antibody
  • Kv1 antibody
  • Kv1.5 antibody
  • PCN1 antibody

Protein level used designations for KCNA5

potassium voltage-gated channel, shaker-related subfamily, member 5 , potassium voltage-gated channel subfamily A member 5-like , cardiac potassium channel , insulinoma and islet potassium channel , potassium channel 1 , potassium voltage-gated channel subfamily A member 5 , voltage-gated potassium channel HK2 , voltage-gated potassium channel protein Kv1.5 , voltage-gated potassium channel subunit Kv1.5 , KV1-5 , Potassium (K+) channel protein alpha 5 , RCK7 , RK4 , potassium voltage gated channel, shaker related subfamily, member 5 , shaker subfamily potassium channel Kv1.5 alpha subunit , delayed rectifier K+ channel , Kv1.5 potassium channel , potassium voltage-gated channel shaker-related subfamily member 5 , potassium voltage-gated channel shaker-related subfamily 5 , potassium channel Kv1.5 , voltage-gated potassium channel Kv1.5

GENE ID SPECIES
466930 Pan troglodytes
496997 Xenopus (Silurana) tropicalis
100431806 Pongo abelii
3741 Homo sapiens
16493 Mus musculus
25470 Rattus norvegicus
395115 Gallus gallus
403995 Canis lupus familiaris
474166 Sus scrofa
508960 Bos taurus
100008684 Oryctolagus cuniculus
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