This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
KCNA5 antibody, kcna5 antibody, ATFB7 antibody, HCK1 antibody, HK2 antibody, HPCN1 antibody, KV1.5 antibody, PCN1 antibody, Kv1.5 antibody, Kv1 antibody, potassium voltage-gated channel subfamily A member 5 antibody, potassium channel, voltage gated shaker related subfamily A, member 5 antibody, potassium voltage-gated channel, shaker-related subfamily, member 5 antibody, KCNA5 antibody, kcna5 antibody, Kcna5 antibody
Background
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. [provided by RefSeq].