anti-Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) Antibodies

P4HA1 encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. Additionally we are shipping P4HA1 Kits (21) and P4HA1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P4HA1 18451 Q60715
P4HA1 5033 P13674
P4HA1 64475 P54001
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Top anti-P4HA1 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN190847 (0.2µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.62
Details
Human Goat Un-conjugated ELISA, IHC (p), WB Western Blot: P4HA1 Antibody [ABIN252918] - ABIN252918 (0.2µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: P4HA1 Antibody [ABIN2529182] - Analysis of P4HA1 in HEK293 cell lysate (35ug protein in RIPA buffer) using ABIN2529182 at 0.1ug/ml. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: P4HA1 Antibody [NBP1-84398] - Staining of human cell line U-2 OS shows positivity in endoplasmic reticulum & vesicles. Western Blot: P4HA1 Antibody [NBP1-84398] - Lane 1: NIH-3T3 cell lysate (Mouse embryonice fibroblast cells). Lane 2: NBT-II cell lysate ( Rat Wistar bladder tumour cells). 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with P4HA1 antibody ABIN461984 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Spleen (formalin-fixed, paraffin-embedded) stained with P4HA1 antibody ABIN461984 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with P4HA1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Spleen (formalin-fixed, paraffin-embedded) stained with P4HA1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$390.50
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of rat skin tissue, using P4HA1 antibody. ABIN6273063 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-P4HA1 Antibodies

  1. Human Polyclonal P4HA1 Primary Antibody for ELISA, IHC (p) - ABIN252918 : Van Duyn Graham, Sweetwyne, Pallero, Murphy-Ullrich: Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix. in The Journal of biological chemistry 2010 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal P4HA1 Primary Antibody for WB - ABIN518574 : Ma, Guo, Liu, Liu, Hu, Sun, Yu, Lammi: Proteomic changes in articular cartilage of human endemic osteoarthritis in China. in Proteomics 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against P4HA1 Interaction Partners

Mouse (Murine) Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) interaction partners

  1. Overexpression of P4Ha1 increased atherosclerotic plaque size.

  2. IL-6 (show IL6 Antibodies) destabilizes atherosclerotic plaques by downregulating P4Halpha1 via an RAF-MEK1/2-ERK1/2 MAPK and c-Jun pathway.

  3. C-P4H alpha(I) and alpha(II (show GSTA3 Antibodies)) mRNA levels were increased in hypoxic mouse chondrocytes in a manner dependent on HIF-1a (show HIF1A Antibodies).

Human Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) interaction partners

  1. High expression of P4HA1 was correlated with the malignancy of gliomas and could serve as a prognostic indicator for patients with high-grade gliomas

  2. Our study indicates that P4HA1 plays a pivotal role in the process of GSC (show GSC Antibodies)-EC transdifferentiation and the structural formation of vascular BMs.

  3. we report compound heterozygous frameshift and splice site mutations in P4HA1 that impair but not abolish C-P4H alpha(I) activity. The maternal P4HA1 exon 12 splice donor site mutation causes an internally deleted C-P4H alpha(I) predicted to completely lack catalytic activity. two nucleic acid insertion in exon 9 results in a premature stop in the exon 9 P4HA1 splice form.

  4. Findings suggest that the catalytic domain of collagen prolyl 4-hydroxylases (CP4Hs) recognizes the cis (show CISH Antibodies) conformation of the prolyl peptide bond.

  5. Thus, we conclude that miR (show MLXIP Antibodies)-30e suppresses proliferation of hepatoma cells through targeting P4HA1 mRNA.

  6. Studies indicate P4HA1 copy number gain in a subset of metastatic prostate tumors and its expression is also regulated by microRNA-124.

  7. Overexpression of miR (show MLXIP Antibodies)-122 markedly attenuated the expression of P4HA1 via targeting a binding site located at 3'-UTR (show UTS2R Antibodies) of P4HA1 mRNA

  8. Hypoxia-inducible factor 1 (HIF-1 (show HIF1A Antibodies)) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2 (show P4HA2 Antibodies), and PLOD2 (show PLOD2 Antibodies) expression in fibroblasts.

  9. IL-6 (show IL6 Antibodies) significantly downregulated P4Halpha1 expression in aortic smooth muscle cells

  10. analysis of the 2-His-1 (show HTN1 Antibodies)-Asp (show ASIP Antibodies) active-site motif in prolyl 4-hydroxylase

P4HA1 Antigen Profile

Protein Summary

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with P4HA1

  • prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ000975) antibody
  • prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ017131) antibody
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_03346) antibody
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_03347) antibody
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_15957) antibody
  • prolyl 4-hydroxylase subunit alpha 1 (P4HA1) antibody
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (P4ha1) antibody
  • prolyl 4-hydroxylase subunit alpha 1 (P4ha1) antibody
  • AL022634 antibody
  • P4ha antibody
  • PHalphaI antibody

Protein level used designations for P4HA1

prolyl 4-hydroxylase subunit alpha-1 , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I , prolyl 4-hydroxylase alpha subunit , prolyl 4-hydroxylase, alpha I subunit , 4-PH alpha-1 , procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1 , C-P4Halpha(I) , collagen prolyl 4-hydroxylase alpha(I) , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide

GENE ID SPECIES
6031971 Culex quinquefasciatus
6051272 Culex quinquefasciatus
10909085 Trichinella spiralis
10909086 Trichinella spiralis
10909998 Trichinella spiralis
100037299 Sus scrofa
450891 Pan troglodytes
18451 Mus musculus
5033 Homo sapiens
479242 Canis lupus familiaris
64475 Rattus norvegicus
518288 Bos taurus
423704 Gallus gallus
100172658 Pongo abelii
Selected quality suppliers for anti-P4HA1 (P4HA1) Antibodies
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