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Involved in embryo hatching and implantation..
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Hypothyroidism induces a significant reduction of proteases Isp1 and Isp2 gene expression and Notch (show NOTCH1 ELISA Kits) signaling.
ISP2 is a monomeric enzyme with mixed serine proteolytic activity and can silence signaling via proteinase activated receptors.
the ISP1 and ISP2 genes are co-expressed within the endometrial gland
ISP2 may play an important role during embryo implantation.
organization, structure and postulated function of the implantation serine proteinase (ISP1 and 2) genes.
ISP2 plays a critical role in embryo hatching and implantation
analysis of two rat genes registered in GenBank, accession nos. XM_220240 and XM_577076, exhibited high identities to the mouse ISP2 genes, at an mRNA level
Involved in embryo hatching and implantation.
, implantation serine protease 2
, implantation serine proteinase 2
, serine protease 29
, strypsin-related protein
, tryptase-like proteinase