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Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.. Additionally we are shipping Proteinase 3 Antibodies (199) and Proteinase 3 Proteins (26) and many more products for this protein.
Showing 10 out of 48 products:
Human PRTN3 ELISA Kit for Sandwich ELISA - ABIN457063
Salgado, Pereiro, López-Doval, Lafuente: Initial study on the possible mechanisms involved in the effects of high doses of perfluorooctane sulfonate (PFOS) on prolactin secretion. in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2015
Human PRTN3 ELISA Kit for Sandwich ELISA - ABIN417639
Türko?lu, Azars?z, Emingil, Kütükçüler, Atilla: Are proteinase 3 and cathepsin C enzymes related to pathogenesis of periodontitis? in BioMed research international 2014
Studies indicate that the premature activation of proteinase 3 (PR3) would seriously harm the cell by its protease activity.
this study shows that transgenic mice expressing human Proteinase 3 exhibit sustained neutrophil-associated peritonitis
unique structural and functional characteristics of PR3 might be key contributors to the systemic inflammation and to the immune dysregulation observed in granulomatosis with polyangiitis.
Our findings demonstrate how RAGE-PR3 interactions between human prostate cancer cells and the bone marrow microenvironment mediate bone metastasis during prostate cancer progression
PRTN3 variants are associated with ANCA-associated vasculitis risk.
Clinical manifestations varied ANCA-associated vasculitis categories, and neither MPO-ANCA nor PR3-ANCA significantly affected relapse of AAV.
Changes in the DNA methylation status of the PRTN3 promoter may predict the likelihood of stable remission and explain autoantigen gene regulation
Study shows that MPO (show MPO ELISA Kits) and PRTN3 in neutrophils of Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) patients with active disease have a distinct pattern of histone modifications, which implicates epigenetic mechanisms in regulating expression of autoantigen genes and suggests that the epigenome may be involved in AAV pathogenesis.
The levels of both NE and PR3 correlated with absolute neutrophil counts and are reduced in type 1 diabetes mellitus patients.
Report prognostic value of proteinase-3-antineutrophil cytoplasmic antibody in patients with idiopathic interstitial pneumonias.
Results provide evidence that proteinase 3 as a new factor involved in non-alcoholic fatty liver disease and insulin (show INS ELISA Kits) resistance.
In different murine models of apoptotic cell injection, the PR3-induced microenvironment instructed pDC-driven Th9/Th2 cell generation.
PR3-ANCA is a promising biomarker in primary sclerosing cholangitis.
Proteinase 3-mediated caspase-3 (show CASP3 ELISA Kits) activation controls neutrophil spontaneous death
Increased PRTN3 activity was associated with development of autoimmune diabetes mellitus in NOD mice.
Phagocytosis of apoptotic PR3-expressing cells potentiates proinflammatory cytokines in vivo by resident murine peritoneal macrophages.
the dual functions (activation/termination) of PR3 in IL-33 (show IL33 ELISA Kits) biological activity.
pathogenic effect of proteinase 3-specific antineutrophil cytoplasmic autoantibodies at local sites of inflammation.
Murine and human proteinase 3 complexes have different interaction patterns with peptidic substrates.
PR3 and neutrophil elastase (show ELANE ELISA Kits) enhance neutrophil-dependent inflammation by eliminating the local antiinflammatory activity of progranulin (show GRN ELISA Kits). Our results support the use of serine protease (show F2 ELISA Kits) inhibitors as antiinflammatory agents.
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
, C-ANCA antigen
, Wegener granulomatosis autoantigen
, azurophil granule protein 7
, leukocyte proteinase 3
, neutrophil proteinase 4
, serine proteinase, neutrophil
, wegener autoantigen